Capsule for treating alcoholic cardiomyopathy and preparation method thereof

Abstract

The invention discloses a capsule for treating alcoholic cardiomyopathy and a preparation method thereof. The capsule is applied to the therapy of alcoholic cardiomyopathy. The preparation method is characterized by comprising the steps of (1) distilling Gastrodia elata Bl., Stachys kouyangensis (Van.) Dunn and Sophora flavescens Ait. by water vapor, so as to extract volatile oil for later use, and enabling dregs to be standby; (2) crushing Gekko gecko Linnaeus and Setaria italica (L.) Beauv. into fine powder for later use; (3) uniformly mixing Selaginella tamariscina (Beauv.) Spring, Begonia handelii Irmsch., Poncirus tuifoliata (L.) Raf., Polygonum aviculare L., Ranunculus ternatus Thunb., Dracocephalum moldavica L., Callicarpa nudiflora Hook. Et Arn. and the dregs obtained in the step (1), carrying out ethanol extraction twice, merging two alcohol extracts, filtrating, recovering ethanol, and carrying out depressurized concentration, so as to form an extract; (4) adding the fine powder obtained in the step (2) into the extract obtained in the step (3), uniformly mixing, drying at the temperature of 60 DEG C, crushing into fine powder, adding polysorbate-80, granulating, drying, finishing, spraying the volatile oil obtained in the step (1), uniformly mixing, and encapsulating, thereby obtaining the capsule. Proved by clinical trials, the capsule has the characteristics of good treatment effect and relatively high safety in the therapy of alcoholic cardiomyopathy, so that the capsule is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a capsule for treating alcoholic cardiomyopathy and a preparation method thereof. Background technique [0002] The onset of alcoholic cardiomyopathy (ACM) is closely related to long-term heavy alcohol intake, and it mostly occurs in men aged 30 to 55, usually with a history of excessive drinking for more than 10 years, with diverse clinical manifestations, the main manifestations Cardiac insufficiency and arrhythmia, including heart enlargement, congestive heart failure, arrhythmia, chest pain, blood pressure changes and other main symptoms. [0003] Alcoholic cardiomyopathy is the result of direct toxicity of ethanol and its metabolite acetaldehyde to the myocardium. The direct toxic effect of alcohol on cardiomyocytes is mainly manifested in the following aspects: ①Ethanol damages the integrity of the myocardial cell membrane, increases the permeability of the cel...

AI Technical Summary

Problems solved by technology

However, the current clinical treatment is mostly based on the treatment of deficiency syndromes, and those with excess syndromes should be rehabilitated, resulting in twice the result with half the effort.