Microencapsulated multi-vitamin premix and preparation method thereof

Abstract

The invention relates to a type of microencapsulated multi-vitamin premix and a preparation method of the microencapsulated multi-vitamin premix and mainly relates to the field of agricultural biotechnologies and feed additives. The preparation method of the microencapsulated multi-vitamin premix is used for improving the uniformity of the multi-vitamin premix and the stability of multiple vitamins. According to the formula of the microencapsulated multi-vitamin premix, the microencapsulated multi-vitamin premix contains PEG, vitamin A, vitamin D3, vitamin E, vitamin K3 (MNB), vitamin B1, vitamin B2, vitamin B6, vitamin B12, folic acid, biotin, nicotinamide and calcium pantothenate. The preparation method includes the three steps of PEG fusion, homogenous emulsification and spraying condensation and is simple in process and easy to operate. The multi-vitamin premix produced with the preparation method is actually an interstitial solid solution, the vitamins are evenly distributed in the form of microcrystals or amorphous powder, the grading phenomenon is avoided in the transportation process, and the multi-vitamin premix is good in stability and thus can not be damaged easily in the storage and feed processing processes. In comparison with multi-vitamin premix produced with a traditional direct mixing method, the addition amount of the microencapsulated multi-vitamin premix prepared with the method in mixed feed can be reduced by 35-50%, and the production performance level of animals will not be affected.

Description

technical field [0001] The invention relates to a preparation method of a microencapsulated compound vitamin premix, which is mainly used for improving the uniformity of the compound vitamin premix and the stability of various vitamins, and mainly relates to the fields of agricultural biotechnology and feed additives. Background technique [0002] Vitamins are a type of low-molecular nutrients necessary for maintaining normal metabolism, growth and production of animals. They account for a small proportion of feed costs, but play a pivotal role. Vitamins participate in the absorption, utilization and deposition of various nutrients in the form of coenzymes. Without vitamins, the utilization of energy and protein by animals will be limited. Due to the extremely low content of vitamins in raw materials for livestock and poultry feed, the availability of vitamins is poor, so it is necessary Additional supplementation can achieve the purpose of promoting production performance, ...

AI Technical Summary

Problems solved by technology

[0003] At present, the main method of producing multivitamin premixes is to directly mix various powdery vitamin raw materials with carriers such as corn flour, rice husk powder, and corncob powder. The multivitamin premixes produced by this method have the following problems: (1) mixing The uniformity is not ideal. Even if the most advanced mixing equipment is used, it can only ensure that the coefficient of variation of the mixing uniformity is less than 5%. Different samples from the same batch of products have certain differences in vitamin content; (2) The quality of multivitamin premix products To a large extent, it is affected by the physical and chemical properties of the carrier, such as moisture content, particle size, bulk density, fluidity, and pH value; (3) the multivitamin premix produced by the mixing method is prone to grading during transportation; (4) the effect of vitamins on temperature and pressure , metal ions, and oxidants are sensitive, and the vitamins in the multivitamin premix produced by the mixing method are attached to the surface of the carrier and are in a bare state, which is easily damaged during feed processing and storage

Due to its stable chemical properties and good compatibility with organic substances, PEG is often used as a matrix for dripping pills, suppositories, and tablets in the pharmaceutical industry, but it has not been studied and applied in the feed industry.

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