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A pharmaceutical composition for treating fish gill rot and its preparation method

A technology of fish gill rot disease and composition, applied in the field of traditional Chinese medicine for treating fish diseases, capable of solving fish and human health hazards and other problems, achieving a simple and easy preparation method, suitable for large-scale production, prevention and treatment of gill rot Effect of disease

Active Publication Date: 2016-05-11
泰州市春达动物药业饲料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to solve the gill rot disease, many of them are treated with western medicine, which has caused great harm not only to fish, but also to human health.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A pharmaceutical composition for treating gill rot of fish, comprising the following traditional Chinese medicines in parts by weight: 10 parts of Tripterygium wilfordii, 10 parts of gall, 15 parts of Dijincao, 5 parts of neem leaves, 10 parts of Houttuynia cordata, 5 parts of natural lotus.

[0025] The preparation method of described pharmaceutical composition comprises the following steps:

[0026] 1) Weigh 10 parts of Tripterygium wilfordii plus 10 times 80% ethanol, and use supercritical CO 2 Extract the active ingredients of Tripterygium wilfordii;

[0027] 2) Weigh 15 parts of Dijincao and add 10 times the amount of 75% ethanol to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0028] 3) Weigh 5 parts of neem leaves, 10 parts of Galla chinensis, 20 parts of Houttuynia cordata, 10 parts of chrysanthemum lotus, add 20 times of water to decoct for 2 hours, filter to obtain the supernatant;

...

Embodiment 2

[0034] A pharmaceutical composition for treating gill rot of fish, comprising the following traditional Chinese medicines in parts by weight: 30 parts of Tripterygium wilfordii, 20 parts of Galla gall, 30 parts of Dijincao, 10 parts of Neem leaves, 25 parts of Houttuynia cordata, 15 parts of natural lotus.

[0035] The preparation method of described pharmaceutical composition comprises the following steps:

[0036] 1) Weigh 30 parts of Tripterygium wilfordii plus 15 times 80% ethanol, and use supercritical CO 2 Extract the active ingredients of Tripterygium wilfordii;

[0037] 2) Weigh 30 parts of Dijincao and add 15 times the amount of 75% ethanol to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0038] 3) Weigh 10 parts of neem leaves, 120 parts of Chinese gallnut, 25 parts of Houttuynia cordata, 15 parts of chrysanthemum lotus, add 25 times of water and decoct for 4 hours, filter to obtain the supe...

Embodiment 3

[0044] A pharmaceutical composition for treating gill rot of fish, comprising the following traditional Chinese medicines in parts by weight: 20 parts of Tripterygium wilfordii, 15 parts of Galla gall, 22 parts of Dijincao, 7 parts of Neem leaves, 17 parts of Houttuynia cordata, 13 parts of natural lotus.

[0045] The preparation method of described pharmaceutical composition comprises the following steps:

[0046] 1) Weigh 20 parts of Tripterygium wilfordii plus 13 times 80% ethanol, and use supercritical CO 2 Extract the active ingredients of Tripterygium wilfordii;

[0047] 2) Weigh 20 parts of Dijincao and add 13 times the amount of 75% ethanol to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Dijincao;

[0048] 3) Weigh 7 parts of neem leaves, 15 parts of Galla gall, 23 parts of Houttuynia cordata, 13 parts of chrysanthemum lotus, add 23 times of water and decoct for 3 hours, filter to obtain the supernatant;...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating gill rot disease of fish, which comprises the following traditional Chinese medicines in parts by weight: 10-30 parts of Tripterygium wilfordii, 10-20 parts of Chinese gall, 15-30 parts of Dijincao, neem azalea 5~10 parts of leaves, 10~25 parts of Houttuynia cordata, and 5~15 parts of natural lotus. The invention also discloses a preparation method of the pharmaceutical composition. A pharmaceutical composition for treating fish gill rot disease provided by the present invention, in which Dijincao, neem leaves, and Houttuynia cordata have antibacterial and bacteriostatic effects, and these as active ingredients can well prevent and treat gill rot disease . In the preparation method of the present invention, the active ingredients of Tripterygium wilfordii are extracted by using a supercritical CO2 extraction method, which not only keeps the activities of triptolide, tripteryglide and total alkaloids, but also has relatively high content. The preparation method of the invention is simple and easy, and is suitable for large-scale production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine for treating fish diseases, in particular to a pharmaceutical composition for treating fish gill rot and a preparation method thereof. Background technique [0002] The average incidence of gill rot in fish in aquatic animals is more than 50%, and sometimes it reaches more than 90%. In order to solve the gill rot disease, many of them are treated with western medicine, which has caused great harm not only to fish but also to human health. Therefore the research of the Chinese herbal medicine of Chinese herbal medicine prevention and treatment gill rot is also increasingly important. [0003] Tripterygium wilfordii is the root of the Euonymus plant Tripterygium wilfordii, also known as yellow rattan, yellow wax rattan, vegetable insect medicine, red medicine, and water mangcao. It is mainly produced in Fujian, Zhejiang, Anhui, Henan and other places. The original plants were born in sh...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/78A61P31/04
Inventor 房元喧王松刚
Owner 泰州市春达动物药业饲料有限公司
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