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Test card for detecting human glycated albumin

A technology of glycosylated albumin and albumin, which is applied in the direction of biological testing, material inspection products, etc., can solve the problems of large changes in HbA1c, and achieve the effect of simple control, avoiding inconvenience and danger

Inactive Publication Date: 2013-12-04
TIANJIN HUASHENGYUAN TECH
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Problems solved by technology

However, HbA1c can also increase in diseases other than diabetes, such as uremia, hyperthyroidism, renal failure, etc., when hemolytic anemia, hemoglobin variants such as Hbs or Hbc, and hyperHbfemia, HbA1c changes greatly due to the decline in red blood cell lifespan

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  • Test card for detecting human glycated albumin
  • Test card for detecting human glycated albumin

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Embodiment Construction

[0014] The present invention will be further described below in conjunction with specific examples.

[0015] A dual-channel test card for detecting human glycated albumin, in which a sample pad 1, a conjugation pad, a nitrocellulose membrane and an absorbent pad 4 are sequentially adhered to a PVC backing 7; the conjugation pad consists of the first conjugation pad 2 and The second binding pad 8 is composed of the monoclonal antibody A of glycated albumin labeled with a marker or the nucleic acid aptamer B of glycated albumin labeled with a marker on the first binding pad 2; Mat 8 is coated with a monoclonal antibody C of albumin marked by a marker or an aptamer D of albumin marked by a marker, and the nitrocellulose membrane is composed of the first nitrocellulose membrane 3 and The second nitrocellulose membrane 9 is composed of a first detection line 5 and a first quality control line 6 on the first nitrocellulose membrane 3, and the first detection line 5 is coated with th...

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Abstract

The invention discloses a binary-channel test card for detecting a human glycated albumin. The binary-channel test card is characterized in that a sample pad, a bonding pad, a cellulose nitrate membrane and a water absorption pad are orderly adhered to a PVC backing; special monoclonal antibodies and aptamers of a human glycated albumin and an albumin are used as detection reagents and are used for detecting content of the human glycated albumin and the total albumins. The binary-channel test card can detect a ratio of the glycated albumin to the total albumins in a human biological sample such as a blood sample and a saliva sample, utilizes saliva replacing blood to carry out non-invasive detection, and prevents inconvenience and danger of blood sampling. The binary-channel test card is convenient for fast, accurate and simple control and monitoring of a blood sugar level.

Description

technical field [0001] The invention relates to the field of biological detection, in particular to a test card and method for detecting human glycated albumin. Background technique [0002] As the incidence of diabetes increases year by year, the population of diabetic patients gradually expands, and China has become the second diabetic country after India. According to WHO epidemiological survey statistics, according to the current growth rate of diabetes, the worldwide population of diabetes will reach 300 million from 130 million in 1995 by 2025. The late stage of diabetes can cause many serious complications such as the retina, kidney, and nerves, which seriously threaten people's health. It is very difficult to cure completely. Strictly controlling blood sugar levels is an effective means to treat diabetes and prevent its various complications. People have realized the importance of fasting and 2-hour postprandial blood glucose monitoring, and often regard the measure...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68
Inventor 吴淑庆徐俊弓景波杨志华曹伟
Owner TIANJIN HUASHENGYUAN TECH
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