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Cleanser for full-automatic biochemical analyzer and preparation method thereof

A biochemical analyzer and cleaning agent technology, applied in the field of cleaning agents, can solve the problems of unsatisfactory application effect of cleaning agents, carrying pollution, and large damage load of the flow path system, achieving good cleaning effect, small environmental load, and meeting environmental protection requirements. Effect

Inactive Publication Date: 2013-09-04
SUZHOU KANGHESHUN MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The actual application effect of cleaning agents produced and supplied in China is not ideal. Many manufacturers pursue the cleaning effect one-sidedly, and even add too many surfactant components or strong acid / alkali to improve the cleaning effect, so that the cleaning agent will damage the flow system of the instrument. The load is very large, and there is a case of carrying pollution brought by the cleaning agent, so many products still cannot meet the needs of users

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: First, take 650mL of pure water with a measuring cylinder, then slowly add 100g of potassium hydroxide into it to dissolve and stir evenly, then transfer it into a 1L volumetric flask. After cooling, slowly add 100mL potassium hypochlorite solution, stir for 20 minutes, then add 100g potassium chloride, set the volume to 1L, and stir evenly to obtain 1 liter of stable cleaning agent for automatic biochemical analyzer.

[0026] Use Hitachi 7600 automatic biochemical analyzer to test the cleaning performance of the above-mentioned acid cleaning agent. The test indicators include the residual rate of protein substances, the residual rate of lipid substances, the deposition of reactants, the intra-batch repeatability of clinical projects, cross-contamination, especially glycerin three Cross-contamination of ester reactants, correlation of measurement results when using original acidic cleaning agents, etc.

[0027] In the test results, all performance test indica...

Embodiment 2

[0028] Example 2: first take 650mL of pure water with a measuring cylinder, then slowly add 200g of potassium hydroxide into it to dissolve and stir evenly, then transfer it into a 1L volumetric flask. After cooling, slowly add 200mL of potassium hypochlorite, stir for 20 minutes, then add 200g of potassium chloride, set the volume to 1L, and stir evenly to obtain 1L of stable cleaning agent for automatic biochemical analyzer.

[0029] Use Hitachi 7600 automatic biochemical analyzer to test the cleaning performance of the above-mentioned acid cleaning agent. The test indicators include the residual rate of protein substances, the residual rate of lipid substances, the deposition of reactants, the intra-batch repeatability of clinical projects, cross-contamination, especially glycerin Cross-contamination of triester reactants, correlation of measurement results when using original acidic cleaning agents, etc.

[0030] In the test results, all performance test indicators are wit...

Embodiment 3

[0031] Example 3: first take 650mL of pure water with a measuring cylinder, then slowly add 100g of sodium hydroxide into it to dissolve and stir evenly, then transfer it into a 1L volumetric flask. After cooling, slowly add 100mL of sodium hypochlorite, stir for 20 minutes, then add 100g of sodium chloride, set the volume to 1L, and stir evenly to obtain 1 liter of stable cleaning agent for automatic biochemical analyzer.

[0032] Use Hitachi 7600 automatic biochemical analyzer to test the cleaning performance of the above-mentioned acid cleaning agent. The test indicators include the residual rate of protein substances, the residual rate of lipid substances, the deposition of reactants, the intra-batch repeatability of clinical projects, cross-contamination, especially glycerin Cross-contamination of triester reactants, correlation of measurement results when using original acidic cleaning agents, etc.

[0033]In the test results, all performance test indicators are within t...

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Abstract

The invention relates to a cleanser for a full-automatic biochemical analyzer and a preparation method thereof. The cleanser comprises the following components in percentage by weight: 10-20% of at least one inorganic alkali, 2-8% of at least one hypochlorite, 10-20% of at least one inorganic salt and the balance of water. In the cleanser, the inorganic alkali is potassium hydroxide or sodium hydroxide, the hypochlorite is postassium hypochlorite or sodium hypochlorite, and the inorganic salt is potassium chloride or sodium chloride. The cleanser provided by the invention has the characteristics of favorable in-batch repetitiveness of clinical detection projects, low cross contamination and low reactant deposition, does not have any corrosive action on the reaction cup and flow path system of the analyzer in the cleaning process, does not have potential pollution on the environment, and satisfies the requirement for environmental protection.

Description

technical field [0001] The invention relates to a cleaning agent, in particular to a cleaning agent used by a fully automatic biochemical analyzer when analyzing samples (including serum, plasma, urine, cerebrospinal fluid, etc.) and a preparation method thereof. Background technique [0002] The automatic biochemical analyzer is an instrument for measuring a specific chemical composition in body fluids (including serum, plasma, urine, cerebrospinal fluid, etc.) based on the principle of photoelectric colorimetry. and health status. Due to its fast measurement speed, high accuracy, and small consumption of reagents, the number of fully automatic biochemical analyzers in the world, especially in China, is increasing year by year. Now it is used in hospitals at all levels in my country, epidemic prevention Websites and family planning service stations are widely used. The test accuracy of the automatic biochemical analyzer directly affects the doctor's diagnosis results, so it ...

Claims

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Application Information

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IPC IPC(8): C11D7/60C11D7/10
Inventor 李晴
Owner SUZHOU KANGHESHUN MEDICAL TECH
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