Animal motion sickness inducing device

Abstract

Provided is an animal motion sickness inducing device. The problem that simple stimulation-induced modeling and diversified experiment factors of rodent motion sickness in the prior art influence determination data and enable the data to be unreliable and the like is solved. The animal motion sickness inducing device comprises a base, a rotary table assembled on the base through a rotary shaft and used for driving an experimental animal to move and a drive device. The technical point is that at least two animal limiting movement devices are fixed on the rotary table, and each animal limiting movement device comprises a support, a base provided with an excrement collecting trough, a walking mechanism fixed on the base, a trunk limiting cover and a head fixing device. The rotary shaft is assembled on the base through a bearing seat, and a rotary shaft drive device comprises a motor, a driven wheel fixed on the rotary shaft, a driving wheel driven by the motor and a transmission belt tensioned on the driving wheel and the driven wheel. The animal motion sickness inducing device is reasonable in structural design, convenient to operate, safe and reliable in use, effectively establishes an animal experimental model inducing the motion sickness and facilitates control of research, development and screening of anti-motion-sickness drugs and guidance of clinical treatment.

Description

technical field [0001] The present invention relates to an animal experimental model for inducing motion sickness, in particular to an animal motion sickness inducing device established under the mismatch condition of vision-vestibular sensation-proprioception, which is mainly used to induce motion sickness from different sides To reveal the mechanism of motion sickness, develop and screen anti-sickness drugs based on this mechanism, and guide the clinical treatment of motion sickness. Background technique [0002] Motion sickness is a syndrome in which the body cannot adapt to the stimulation of acceleration, vision and deep sensation, such as dizziness, dizziness, nausea, vomiting, cold sweat, pale complexion, etc., which mainly respond to vestibular organs and autonomic nerves, including motion sickness, seasickness, airsickness, etc. The mechanism of motion sickness has not yet been fully elucidated because the stimulation process is affected by multiple and complex fact...

AI Technical Summary

Problems solved by technology

[0006] The object of the present invention is to provide a kind of animal motion sickness inducing device, has solved the problems such as single stimulus-induced modeling of rodent motion sickness in the prior art, multiple experimental factors influence measurement data unreliable, etc., its structural design Reasonable, easy to operate, safe and reliable to use, effectively established an animal experimental model of motion sickness induced by visual-vestibular-proprioceptive mismatch conditions, improved the accuracy of measurement data, and revealed the occurrence of motion sickness from different aspects Mechanism, which facilitates the control of research and development and screening of anti-sickness drugs and helps to guide the clinical treatment of motion sickness

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