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Device and method for the detection of a fungal contamination in ambient air

一种检测室、检测模块的技术，应用在支持/固定微生物的方法、特定用途的生物反应器/发酵罐、测量装置等方向，能够解决无法满足真菌污染早期检测和连续监测的需求、耗时、高成本等问题

Active Publication Date: 2013-07-24
SCI & TECH CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These steps for detecting fungal contamination in indoor environments require the intervention of qualified technicians and are quite time-consuming and costly
Therefore, these analytical techniques do not allow rapid and continuous determination of
[0014] Therefore, currently available solutions cannot meet the need for early detection and continuous monitoring of fungal contamination

Method used

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  • Device and method for the detection of a fungal contamination in ambient air
  • Device and method for the detection of a fungal contamination in ambient air
  • Device and method for the detection of a fungal contamination in ambient air

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0124] Example 1: First embodiment of the device

[0125] The preconcentrator module consists of micro preconcentrators etched on a silicon plate by DRIE process. The micro-preconcentrator consists of 20 grooves 6 cm long, with a rectangular cross-section 500 μm wide, 250 μm long, and 0.15 cm long. 3 effective volume. The groove is filled with 2,6-diphenyl ether (named TA) resin particles, the particles have an average diameter of 120 μm, a specific surface area of ​​35m 2 / g, porosity 2.4cm 3 / g, and an average pore size of 200 nm. The micro preconcentrator is closed by a glass plate bonded to the surface comprising the groove of the first plate.

[0126] Chromatographic microcolumns are etched on silicon plates by DRIE process. The micropillars consisted of 5 m long grooves with a rectangular cross-section 150 μm wide and 200 μm long. The grooves are created in the form of parallel loops (or coils) with turns in the form of arcs to prevent the formation of dead end...

example 2

[0129] Example 2: Microcolumn calibration of the first embodiment

[0130] For the calibration, the sensor array of the device described in Example 1 was replaced by a mass spectrometer.

[0131] Table 1 lists the experimental parameters for the analytical chain.

[0132] Table 1: Characteristic parameter list of GC / MS

[0133]

[0134]

[0135] Target VOC samples were passed through the microcolumns to determine the retention time for each target VOC.

[0136] Table 2 lists the retention times for each target VOC.

[0137] Table 2

[0138]

example 3

[0139] Example 3: Experimental approach

[0140] 3.1 Experimental setup for polymer sensors

[0141] 3.1.A Data Acquisition System

[0142] The experiments were carried out with a system capable of acquiring signals from a card composed of a conductive polymer, which forms the heart of the system.

[0143] The firing cavity is placed outside the system. A filtration system including TENEX catheter Tx is located upstream of the firing chamber and ensures "clean" air make-up (leakage). Downstream of the firing chamber, a PTFE conduit enables the connection between the firing chamber and the three-way solenoid valve. All connections are made of PTFE. A three-way solenoid valve (sold by BIO-CHEM-VALVE Ltd.) makes it possible to select the reference path (air filtered by activated carbon), the sampling path (emission chamber) or the cleaning path (1-butanol / water mixture).

[0144] Pump (ESCAP company sales) can be 147 ± 1mL / min -1 Air in different climates is transport...

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Abstract

This invention relates to a device for detecting fungal contamination in an interior environment, including: a concentration module (MC); a separation module (MS) including a chromatographic microcolumn; and a detection module (MD), characterized in that it includes at least one first solenoid valve (E3) upstream of the detection module (MD) enabling either to direct a flow containing target molecules toward the detection module (MD), or to direct a flow filtered by a first means for filtering (Tx1), enabling the detection module (MD) to be cleaned when the flow does not contain the target molecules. The invention also relates to a control interface of the device.

Description

technical field [0001] The invention relates to a device for detecting fungal contamination in an indoor environment, its use, and a method for implementing such a device for detecting fungal contamination in an indoor environment. Background technique [0002] In industrialized countries, people spend more than 90% of their time in enclosed spaces where they are exposed to numerous physical, chemical and biological pollutants. Aware of the potential health risks caused by these complex pollutions, government authorities have introduced in the national environmental code (Grenelle2environmental code) monitoring regulations for air quality in indoor environments. This law includes the implementation of systems for measuring and providing information in facilities housing vulnerable groups (children, elderly, etc.) and public places (schools, public transport, museums, etc.). Therefore, the World Health Organization (WHO) pointed out in its report "WHO Indoor Air Quality Guid...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/34C12M1/36C12M1/12C12Q1/04
CPCC12Q1/04G01N33/0029G01N33/0047
Inventor S·某乐拉特Y·岳柏林E·罗宾
Owner SCI & TECH CENT
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