Preparation method of pharmaceutical composition for treating dysostosis multiplex
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A multiple, composition technology, applied in the directions of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as lack of curative effect, and achieve the effects of good compliance, pain relief, and convenient taking.
Inactive Publication Date: 2013-06-19
王瑞国
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Abstract
Description
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Problems solved by technology
Therefore, the treatment of this disease with "consolidating the root and nourishing the essence, nourishing the liver and kidney" is bound to fail to obtain good curative effect.
Method used
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Examples
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Embodiment 1
[0035] Example 1, the weight ratio of raw materials: 10 parts of Maolan, 6 parts of kapok bark, 3 parts of poria cocos, 6 parts of tangerine peel, 3 parts of box grass, 6 parts of terrazzo, 6 parts of kudzu root, 6 parts of aescin, 6 parts of loofah, 1 part of Jiulixiang, 3 parts of burnt malt, and 10 parts of burnt grain sprouts.
Embodiment 2
[0036] Example 2, the weight ratio of raw materials: 20 parts of Maolan, 10 parts of kapok bark, 6 parts of poria cocos, 10 parts of tangerine peel, 6 parts of box grass, 10 parts of stellite, 10 parts of kudzu root, 10 parts of aescin, 10 parts of loofah, 2 parts of Jiulixiang, 6 parts of burnt malt, 20 parts of burnt grain sprouts.
Embodiment 3
[0037] Example 3, the weight ratio of raw materials: 30 parts of Maolan, 12 parts of kapok bark, 10 parts of poria cocos, 12 parts of tangerine peel, 10 parts of box grass, 12 parts of terrazzo, 12 parts of kudzu root, 12 parts of aescin, 12 parts of loofah, 5 parts of Jiulixiang, 10 parts of burnt malt, and 25 parts of burnt grain sprouts.
[0038] The Chinese medicine of embodiment 1~3 can be prepared by the following method:
[0039] (1) Extract the volatile oils from kudzu root, kapok bark, and box grass powder by steam distillation, and collect and mix for later use;
[0040] (2) Grind burnt grain buds and burnt malt through a 150-mesh sieve to form fine powder for later use;
[0041] (3) Mix the leaves of Maolan, Poria cocos, tangerine peel, scorpion vine, loofah, aescin, jiulixiang, add 10 times the amount of water, add water to decoct twice, each time for 1 hour, combine the decoction, and let it stand; then Add 3~4 times of 95% ethanol to the decoction, let it stand f...
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PUM
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Abstract
The invention discloses a preparation method of a pharmaceutical composition for treating dysostosis multiplex, which aims to solve the problem of treatment of dysostosis multiplex. The invention is characterized by comprising the following active pharmaceutical ingredients in parts by weight: eria graminifolia Lindl., cotton tree bark, tuckahoe, dried orange peel, Lobed Actinostemma Herb, Trachelospermum jasminoides, kudzu root, Paris polyphylla, retinervus luffae fructus, murraya jasminorage, brown malt and charred rice sprout. The preparation method comprises the following steps: (1) extracting volatile oil from the kudzu root, cotton tree bark and Lobed Actinostemma Herb coarse powder for later use; (2) pulverizing the charred rice sprout into fine powder for later use; (3) extracting the Eria graminifolia Lindl., tuckahoe, dried orange peel, Trachelospermum jasminoides, retinervus luffae fructus, Paris polyphylla, murraya jasminorage and brown malt with water, precipitating with alcohol, and drying to obtain a primary material; and (4) spraying the volatile oil into the primary material, evenly mixing with the charred rice sprout fine powder, passing through a 60-mesh sieve, and encapsulating. The clinical experiment proves that the pharmaceutical composition for treating dysostosis multiplex has the characteristics of good curative effect and high safety, and is worthy of clinical application and popularization.
Description
technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of a medicinal composition for treating multiple abnormal osteogenesis. Background technique [0002] Dysostosis epiphysealis multiplex (DEM) is a genetic defect in the development of cartilage, characterized by abnormal bone formation in multiple bones, ossification growth disorder in patients, thick and short fingers, and it is more common in men than women. The age of onset is infants and adolescents. The hips, shoulders, and ankles are more common, followed by the knees, wrists, and elbows. The main clinical manifestations are pain in the hip and knee joints, limited mobility, difficulty in walking, and a swinging gait. Multiple dysostosis is characterized by epiphyseal stagnation and abnormal ossification: flattened, fragmented, symmetrical epiphyses, short stature, and early-onset osteoarthritis. Pathologically, the developing epiphyseal o...
Claims
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Application Information
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