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Sterilization composition containing triflumizole and dimethomorph and application thereof

A technology of dimethomorph and insecticidal composition, which is applied in the field of fungicidal compositions containing fluconazole and dimethomorph, and can solve problems such as reports on fungicidal compositions of fluconazole and dimethomorph that have not been seen yet , to achieve excellent effect, improve bactericidal activity and increase safety

Active Publication Date: 2014-03-26
上海沪联生物药业(夏邑)股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] So far, there have been no reports on the compounded bactericidal composition of fluconazole and dimethomorph

Method used

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  • Sterilization composition containing triflumizole and dimethomorph and application thereof
  • Sterilization composition containing triflumizole and dimethomorph and application thereof
  • Sterilization composition containing triflumizole and dimethomorph and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Fluconazole 25%, Dimethomorph 25%, Sodium Alkylbenzene Sulfonate 8%, Lauryl Polyoxyethylene Ether 6%, Sucrose 3%, Polyvinylpyrrolidone 3%, Light Calcium Carbonate up to 100% %.

[0027] The mixture is ultrafinely pulverized, then granulated, dried, and sieved to obtain 50% flufenazole·dimethomorph water-dispersible granules with an average particle diameter of about 4 μm.

[0028] By the method similar to embodiment 1 can prepare the following different contents of flufenazole dimethomorph water dispersible granules:

[0029]

[0030]

Embodiment 6

[0032] Fluconazole 25%, dimethomorph 15%, alkyl naphthalene sulfonate 5%, sodium lauryl sulfate 8%, light calcium carbonate to 100%.

[0033] The above-mentioned components are fully mixed, and the mixture is pulverized in a jet mill to obtain 40% flufenazole·dimethomorph wettable powder with an average particle size of 20 μm.

[0034] By the method similar to embodiment 6 can prepare the following different contents of flufenazole dimethomorph wettable powder:

[0035]

Embodiment 11

[0037] Fluconazole 15%, Dimethomorph 15%, Polycarboxylate 6%, Sodium Lauryl Sulfonate 5%, Xylene 8%, Magnesium Aluminum Silicate 3%, Ethylene Glycol 1%, Silicone Defoamer 1%, water to make up to 100%.

[0038] Preparation method: Mix the above-mentioned components uniformly and pulverize them in a ball mill for 4 hours to form a coarse dispersion liquid, and then go through wet ultrafine pulverization to make the average particle size less than 5 μm to obtain the required 30% flufenazole-ene Acylmorpholine Suspending Agent.

[0039] Can prepare the following different contents of flufenazole dimethomorph suspending agent by the similar method of embodiment 11:

[0040]

[0041] In order to verify the performance of the bactericidal composition of the present invention, the inventors further carried out a series of experiments. Due to space limitations, only the most representative data are listed here.

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Abstract

The invention discloses a sterilization composition containing triflumizole and dimethomorph and the application thereof. The sterilization composition utilizes triflumizole and dimethomorph as main effective components with mass ratio of the triflumizole and the dimethomorph being (1-40): (40-1). Content sum of the triflumizole and the dimethomorph is 1-80% of total mass of the sterilization composition. The sterilization composition can be prepared into water dispersible granule, wettable powder or suspending agent which are allowable in agriculture and is mainly used for preventive treatment of powdery mildew, downy mildew, brown rot and the like.

Description

technical field [0001] The invention belongs to the field of insecticides, and in particular relates to a bactericidal composition containing fluconazole and dimethomorph and an application thereof. Background technique [0002] Triflumizole, chemical name: (E)-4-chloro-α,α,α-trifluoro-N-(1-imidazol-1-yl-2-propoxyethylene)-o-toluidine , molecular formula: C 15 h 16 CIF 3 N 3 O, structural formula: [0003] [0004] Fluconazole is a triazole fungicide and an inhibitor of ergosterol demethylation. It has the effects of prevention, treatment and eradication. It has good systemic conductivity, is resistant to rain erosion, and can prevent various crop diseases and insect pests. [0005] Dimethomorph, chemical name: (E,Z)-4-[3-(4-chlorophenyl) 3-(3,4-dimethoxyphenyl)acryloyl]morpholine, molecular formula :C 21 h 22 ClNO 4 , the structural formula: [0006] [0007] Dimethomorph is a fungicide specific for oomycetes. Its action is characterized by destroying the f...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N43/84A01N43/50A01P3/00
Inventor 司贤良
Owner 上海沪联生物药业(夏邑)股份有限公司
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