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Medicinal composition for preventing and treating neuropathic pain

A composition and neurological technology, applied in drug combination, neurological diseases, pharmaceutical formulations, etc., can solve problems such as adverse reactions, achieve significant curative effect and enhance the effect of medicine

Inactive Publication Date: 2013-02-13
TAISHAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Anticonvulsants, opioids, and antidepressants are often used for treatment, but most products are not specific for neuropathic pain, and most of them are ineffective or only moderately relieve pain for most patients, and can cause adverse reactions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1: Pharmaceutical composition for preventing and treating neuropathic pain

[0013] The composition and parts by weight of the bulk drug of the pharmaceutical composition for preventing and treating neuropathic pain are:

[0014] 1 part by weight of magnolanine and 5 parts by weight of ranunculin.

Embodiment 2

[0015] Embodiment 2: the pharmaceutical composition of preventing and treating neuropathic pain

[0016] The composition and parts by weight of the bulk drug of the pharmaceutical composition for preventing and treating neuropathic pain are:

[0017] 10 parts by weight of Magnolin and 10 parts by weight of Ranunculin.

Embodiment 3

[0018] Embodiment 3: the pharmaceutical composition of preventing and treating neuropathic pain

[0019] The composition and parts by weight of the bulk drug of the pharmaceutical composition for preventing and treating neuropathic pain are:

[0020] 4 parts by weight of magnolanine and 5 parts by weight of ranunculin.

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PUM

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Abstract

The invention discloses a medicinal composition for preventing and treating neuropathic pain. The medicine is prepared from magnoflorine and ranunculin which are used as bulk pharmaceuticals in a certain proportion; the medicine can be prepared into various preparations by the conventional preparation process; the defects in the prior art are overcome; the medicinal composition which is used for treating neuropathic pain and is obvious in curative effect and safe is provided; the provided medicine is easy to prepare and low in cost; and the clinical test proves that the medicine has an obvious clinical effect on neuropathic pain comprising prosopalgia, ischialgia, sciatica of nerve roots, postherpetic neuralgia and diabetic peripheral polyneuritis and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a pharmaceutical composition for preventing and treating neuropathic pain. Background technique [0002] Neuropathic pain refers to pain syndromes caused by primary lesions or dysfunctions of the central or peripheral nervous system. It can be caused by trauma or / and disease-induced damage to peripheral nerves, posterior roots of the spinal cord, spinal cord and some parts of the central nervous system above. According to the etiology, nature and degree of nerve injury, it is clinically divided into two categories: central nerve pain and peripheral nerve pain caused by peripheral nerve injury. Central nerve pain, referred to as central pain, is primary pain caused by damage or dysfunction of the pain conduction pathway of the central nervous system. It is commonly seen in spinal cord trauma or cerebrovascular diseases, multiple sclerosis and tumors. Peripheral nerve...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61P25/04A61P25/02A61K31/473
Inventor 孔倩倩
Owner TAISHAN MEDICAL UNIV
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