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Medicine composition for treating diabetes and preparation method thereof

A composition and diabetes technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems such as the lack of a unified syndrome differentiation standard, achieve no toxic and side effects, reduce triglycerides, and have a definite curative effect Effect

Active Publication Date: 2013-01-09
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern doctors have different opinions on the syndrome differentiation and treatm

Method used

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  • Medicine composition for treating diabetes and preparation method thereof
  • Medicine composition for treating diabetes and preparation method thereof
  • Medicine composition for treating diabetes and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0065] Example 1:

[0066] Weigh raw materials according to the following proportions: 8 parts of astragalus, 8 parts of Digupi, 5 parts of white silkworm, 6 parts of cassia seed, 8 parts of salvia miltiorrhiza, 5 parts of coptis, 8 parts of raw land, 5 parts of cornus, 8 parts of yam, Paeonol 5 parts, Poria cocos 8 parts, Alisma 5 parts.

[0067] Preparation method: Take astragalus, Digupi, white silkworm, cassia, salvia, coptis, raw land, cornus, yam, paeonol, poria, Alisma, and add 8 to 12 times the amount to decoct twice according to the formula. After 1-2 hours, filter, combine the secondary extracts, concentrate to 50°C and measure the relative density to 1.15-1.20, add ethanol until the alcohol content reaches 60-70%, let stand overnight, filter the supernatant, Ethanol is recovered under reduced pressure, concentrated into an extract, an appropriate amount of starch is added, mixed evenly, made into granules, dried, and obtained.

[0068] The above-mentioned preparat...

Example Embodiment

[0069] Example 2:

[0070] Weigh the raw materials according to the following proportions: 35 parts of astragalus, 23 parts of digupi, 23 parts of white silkworm, 35 parts of cassia seed, 35 parts of salvia miltiorrhiza, 23 parts of coptis, 35 parts of raw land, 23 parts of cornus, 35 parts of yam, 23 parts of Paeonol, 35 parts of Poria cocos, 23 parts of Alisma.

[0071] Preparation method: Take astragalus, Digupi, white silkworm, cassia, salvia, coptis, raw land, cornus, yam, paeonol, poria, Alisma, and add 8 to 12 times the amount to decoct twice according to the formula. After 1-2 hours, filter, combine the secondary extracts, concentrate to 50°C and measure the relative density to 1.15-1.20, add ethanol until the alcohol content reaches 60-70%, let stand overnight, filter the supernatant, Ethanol is recovered under reduced pressure, concentrated into an extract, an appropriate amount of starch is added, mixed evenly, made into granules, dried, and obtained.

[0072] The...

Example Embodiment

[0073] Example 3:

[0074] Weigh raw materials according to the following proportions: 20 parts of astragalus, 10 parts of Digupi, 10 parts of white silkworm, 20 parts of cassia seed, 20 parts of salvia miltiorrhiza, 10 parts of coptis, 20 parts of raw land, 10 parts of cornus, 20 parts of yam, Danpi 10 parts, Poria cocos 20 parts, Alisma 10 parts.

[0075] Preparation method: Take astragalus, Digupi, white silkworm, cassia, salvia, coptis, raw land, cornus, yam, paeonol, poria, Alisma, and add 8 to 12 times the amount to decoct twice according to the formula. After 1-2 hours, filter, combine the secondary extracts, concentrate to 50°C and measure the relative density to 1.15-1.20, add ethanol until the alcohol content reaches 60-70%, let stand overnight, filter the supernatant, Ethanol is recovered under reduced pressure, concentrated into an extract, an appropriate amount of starch is added, mixed evenly, made into granules, dried, and obtained.

[0076] The above-mentione...

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Abstract

The invention relates to a medicine composition for treating diabetes and a preparation method thereof. The medicine composition comprises Astragalus mongholicus, cortex lycii radicis, white muscardine silkworm, semen cassiae, salviae miltiorrhizae, coptidis rhizome, radix rehmanniae, Fructus corni, etc., and is prepared from a pharmaceutically acceptable carrier or an excipient. The dosage forms of the prepared preparation of the composition comprises granules, tablets, capsules, soft capsules, dripping pills or pills, etc. The medicine composition disclosed herein has the effects of strengthening spleen and tonifying kidney, soothing liver and activating blood circulation, clearing heat and expelling damp, and is suitable for diabetic patients. Clinical research shows that the medicine composition disclosed herein has good effects of reducing fasting hyperglycemia and postprandial hyperglycemia. Experiments show that the medicine composition disclosed herein can obviously the blood sugar of diabetic rats, improve the abnormal sugar tolerance, enhance the sensibility of insulin, and reduce the triglyceride of diabetic rats, and the hypoglycemic effect might be related to the increase of the sensitivity of rats to insulin.

Description

1. Technical field [0001] The invention relates to a pharmaceutical composition for treating diabetes and a preparation method thereof. 2. Background technology [0002] Diabetes is a common clinical disease and frequently-occurring disease. There are about 92.4 million diabetic patients in my country. Chronic hyperglycemia is the third killer of human beings after malignant tumors and cardiovascular and cerebrovascular diseases. Traditional Chinese medicine has accumulated rich experience in the prevention and treatment of type 2 diabetes and its chronic complications, and has certain advantages. Physicians of all dynasties classified diabetes as the category of diabetes. According to the "three eliminations" syndrome differentiation, diabetes is not the same as diabetes. Modern physicians have different opinions on the syndrome differentiation and treatment of diabetes, and have not formed a unified syndrome differentiation standard. [0003] The present invention propo...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P3/10A61K35/64
Inventor 高思华
Owner BEIJING UNIV OF CHINESE MEDICINE
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