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Pharmaceutical composition for treating acute and chronic prostatitis and preparation method thereof

A technology for chronic prostatitis and the composition, applied to the pharmaceutical composition of chronic prostatitis and its preparation, in the treatment of acute field, can solve the problems of general curative effect, high technical requirements, patients feel pain, etc. Simple process, obvious curative effect and exact effect

Inactive Publication Date: 2013-01-02
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current clinical treatment situation is as follows: 1. Systemic antibiotic treatment: Systemic antibiotic treatment has a certain therapeutic effect on prostatitis patients without blockage in the early stage; for patients with blockage and calcification, the effect will not be achieved because the drug can no longer enter the prostate ; and long-term medication is required, resulting in drug resistance, damage to liver, kidney, gastrointestinal function, etc., and causing flora imbalance, increasing the chance of endogenous infection
2. The old-fashioned intra-prostatic injection method: The old-fashioned intra-prostatic injection method has a certain effect on some stubborn prostatitis patients, but the technical requirements are high, the operation is troublesome, the patient feels pain, and it is easy to cause damage to the prostate. Inflammation in the testis and other parts does not work
At the same time, because the pathogenic body cannot be eliminated, it can only be used as an adjuvant therapy.
5. Physiotherapy: Physiotherapy mainly uses the thermal effect generated by physical means to increase the blood circulation of the prostate tissue, accelerate metabolism, and is beneficial to reduce inflammation, eliminate tissue edema, and relieve pelvic floor muscle spasm. Less than the purpose of obvious improvement of symptoms and complete cure
Compared with other methods for treating prostatitis, although traditional Chinese medicine therapy has its obvious advantages, a considerable part of Chinese patent medicines for treating prostatitis has complicated prescriptions, cumbersome processing techniques, high production costs, and unstable curative effects.
For example, the patent number is: ZL200510096360.7, and the invention title is "a Chinese patent medicine for treating acute and chronic prostatitis and its preparation method", which discloses a Chinese medicine for treating acute and chronic prostatitis in men caused by dampness, heat and blood stasis. Patented medicine and its preparation method, the prescription contains 9 or even 10 medicines, the dosage is large, the curative effect is average, and the patient's financial pressure is great

Method used

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  • Pharmaceutical composition for treating acute and chronic prostatitis and preparation method thereof
  • Pharmaceutical composition for treating acute and chronic prostatitis and preparation method thereof
  • Pharmaceutical composition for treating acute and chronic prostatitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Take by weighing the bulk drug according to the following dosage ingredients (consumption is parts by weight)

[0033] Patrinia 70.2 parts, Radix Paeoniae Rubra 23.4 parts, peach kernel 23.4 parts

[0034] 23.4 parts of safflower, 23.4 parts of Zeilan, 23.4 parts of Shiwei

[0035] Preparation:

[0036] Grind Radix Paeoniae Rubra into coarse powder, add 5 times the amount of 95% ethanol aqueous solution, extract 2 times, each time for 2 hours, combine the extracts, filter, and recover the ethanol from the filtrate to concentrate to a relative density of 1.34 (measured at 60°C). Thick ointment, set aside; Patrinia, peach kernel, safflower, eupatorium, Shiwei and alcohol-extracted medicinal residues are added to 10 times the amount of water and decocted twice, each decocting for 2 hours, combined decoction, filtered, Concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.34 (measured at 60°C), add the thick paste of ethanol extract...

Embodiment 2

[0038] Take by weighing the bulk drug according to the following dosage ingredients (consumption is parts by weight)

[0039] Patrinia 75 parts, Radix Paeoniae Rubra 25 parts, peach kernel 25 parts

[0040] 25 parts of safflower, 25 parts of Zeilan, 25 parts of Shiwei

[0041] Preparation:

[0042] Grind Radix Paeoniae Rubra into coarse powder, add 5 times the amount of 95% ethanol aqueous solution, extract twice, each time for 2 hours, combine the extracts, filter, and recover the ethanol from the filtrate to concentrate to a relative density of 1.34 (measured at 60°C). Thick paste, set aside; add Patrinia, peach kernel, safflower, eupatorium, Shiwei and alcohol-extracted medicinal residues to 10 times the amount of water and decoct twice, each time decocting for 2 hours, combine the decoction, filter, Concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.34 (measured at 60°C), add the thick paste of ethanol extract, mix well, dry, pu...

Embodiment 3

[0044]Take by weighing the bulk drug according to the following dosage ingredients (consumption is parts by weight)

[0045] Patrinia 80 parts, Radix Paeoniae Rubra 26.7 parts, peach kernel 26.7 parts

[0046] 26.7 parts of safflower, 26.7 parts of Zeilan, 26.7 parts of Shiwei

[0047] Preparation:

[0048] Grind Radix Paeoniae Rubra into coarse powder, add 5 times the amount of 95% ethanol aqueous solution, extract twice, each time for 2 hours, combine the extracts, filter, and recover the ethanol from the filtrate to concentrate to a relative density of 1.34 (measured at 60°C). Thick paste, set aside; add Patrinia, peach kernel, safflower, eupatorium, Shiwei and alcohol-extracted medicinal residues to 10 times the amount of water and decoct twice, each time decocting for 2 hours, combine the decoction, filter, Concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.34 (measured at 60°C), add the thick paste of ethanol extract, mix well...

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Abstract

The invention provides a pharmaceutical composition for treating acute and chronic prostatitis and a preparation method thereof. The pharmaceutical composition is made from the following drug raw materials: Herba Patriniae 50-100, Radix Paeoniae Rubra (Paeonia lactiflora and / or Paeonia veitchii) 10-35, Semen Persicae (Prunus persica and / or Prunus davidiana) 10-35, Carthamus tinctorius flower 10-35, Lycopus lucidus 10-35, and Folium Pyrrosiae 10-35 parts. The pharmaceutical composition is a pure Chinese medicinal formulation; the effective components and effective fractions of the formula are obtained by the modern full-extraction techniques to achieve the purpose of concentration and refinement to the greatest extent. The pharmaceutical composition has no any toxic or adverse effect, is convenient to administer, and has stable therapeutic effectiveness. The invention also provides the use of the pharmaceutical composition in preparation of drugs for treating acute and chronic prostatitis and related diseases, disorders and syndromes.

Description

technical field [0001] The invention belongs to the technical field of pharmacy. Specifically, the invention relates to a pharmaceutical composition for treating acute and chronic prostatitis and a preparation method thereof. Background technique [0002] Prostatitis is a common disease and frequently-occurring disease in adult males, and it is also one of the more difficult male diseases in clinical diagnosis and treatment. Clinically, it is generally divided into two types: acute prostatitis and chronic prostatitis. The current clinical treatment situation is as follows: 1. Systemic antibiotic treatment: Systemic antibiotic treatment has a certain therapeutic effect on prostatitis patients without blockage in the early stage; for patients with blockage and calcification, the effect will not be achieved because the drug can no longer enter the prostate ; and long-term medication is required, resulting in drug resistance, damage to liver, kidney, gastrointestinal function, ...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P13/08
Inventor 胡小虎王新刚
Owner XIAN CHIHO PHARMA
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