Quality control method for Uighur medicine spikenard strength replenishing preparation

Abstract

The invention belongs to the field of quality control of Uighur medicine preparations, and particularly discloses a quality control method for a Uighur medicine spikenard strength replenishing preparation. The method comprises the following steps of: (1) qualitatively identifying nardosinone and asafetida in the spikenard strength replenishing preparation by using thin layer chromatography respectively; (2) quantitatively detecting total flavone content, total polyphenol content and total polysaccharide content in the spikenard strength replenishing preparation by using spectrophotography respectively; and (3) quantitatively detecting nardosinone content and asafetida content in the spikenard strength replenishing preparation by using high performance liquid chromatography respectively. According to the quality control method, the nardosinone, the total flavone, the total polyphenol, the total polysaccharide and the asafetida in the spikenard strength replenishing preparation are determined in a combined qualitative and quantitative mode, so that the quality of the finished preparation can be effectively and completely controlled and a reliable foundation is provided for clinical application of medicaments. The method has the characteristics of high sensitivity, high repeatability, high stability, accuracy, reliability and the like.

Description

technical field [0001] The invention belongs to the field of quality control of Uyghur medicine preparations, and in particular relates to a quality control method of Uyghur medicine pine tonic preparations. Background technique [0002] "Drug Standards of the Ministry of Health of the People's Republic of China" (Uyghur medicine sub-volume) announced a Songbuli preparation that has the effects of nourishing the heart, calming the nerves, and enhancing gastric function, and is used to treat heart palpitations, neurasthenia, abdominal pain, and stomach problems. The drug is The oral liquid is made from a single herb, Gansong. However, there is only one experiment for its quality control to identify possible terpenoids based on the color reaction. Quantitative analysis methods and limit requirements, and no qualitative and quantitative analysis methods and limit requirements for active monomer compounds, so the original quality control is not targeted, the method is incomplete...

AI Technical Summary

Problems solved by technology

[0002] "Drug Standards of the Ministry of Health of the People's Republic of China" (Uyghur medicine sub-volume) announced a Songbuli preparation that has the effects of nourishing the heart, calming the nerves, and enhancing gastric function, and is used to treat heart palpitations, neurasthenia, abdominal pain, and stomach problems. The drug is The oral liquid is made from a single herb, Gansong. However, there is only one experiment for its quality control to identify possible terpenoids based on the color reaction. Quantitative analysis methods and limit requirements, and no qualitative and quantitative analysis methods and limit requirements for active monomer compounds, so the original quality control is not targeted, the method is incomplete, and it is difficult to effectively achieve the purpose of stably controlling the quality of finished pharmaceuticals. Production and operation have brought difficulties, but also brought hidden dangers to clinical use

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