Flexible eye insert and glucose measuring system

An insert, glucose technology, used in diagnostic recording/measurement, ophthalmic therapy, microsensors, etc., to solve problems such as discomfort

Inactive Publication Date: 2012-10-17
NXP BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, a disadvantage of such lenses is that they require light sources to be directed towards the lens when placed in the patient's eye, which may be considered uncomfortable
Furthermore, it requires the active participation of the patient in monitoring glucose levels, so this entails the risk of non-compliance with the required monitoring regimen

Method used

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  • Flexible eye insert and glucose measuring system
  • Flexible eye insert and glucose measuring system
  • Flexible eye insert and glucose measuring system

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Embodiment Construction

[0049] It should be understood that the drawings are only schematic and not drawn to scale. It should also be understood that the same reference numerals are used throughout the drawings to designate the same or similar parts.

[0050] figure 1 is from Badugu et al. In Current Opinion in Biotechnology (Modern Biotechnology Viewpoint), 16 , 2005, images of the paper on pages 100-107, which discloses a lens comprising several sensor spots 10 including boric acid-doped sensor spots for detecting glucose levels in human tears. point. as in figure 2 As shown in , this paper proposes a reading method in which a separate reader 20 is used to project a flash beam onto a sensor spot 10 and measure the emission intensity of the fluorescent light excited by the flash beam to determine the target analysis concentration of substances such as the concentration of glucose present in the tear fluid of the eye into which the lens has been inserted.

[0051] A variety of boronic acid comp...

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PUM

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Abstract

Disclosed is a flexible insert (100) for placement on the human eye, comprising a light source (110) in said insert such that light emitted from the light source is shielded from the human eye upon correct placement of the insert on the human eye, a light-responsive material (120) placed in the light path of the light source, said light-responsive material emitting light upon stimulation by the light from said light source, the intensity of said stimulated emission being sensitive to a chemical interaction of the light-sensitive material with an analyte of interest, a photodetector (130) for detecting the light emitted by the light-responsive material; and a transmitter (140) coupled to the photodetector for transmitting a photodetector reading. The insert may be used in conjunction with a reader for automated monitoring of an analyte of interest such as glucose in the tear fluid of its wearer.

Description

technical field [0001] The present invention relates to a flexible insert placed on the human eye that can be used to determine the concentration of an analyte of interest, such as glucose in tear fluid. [0002] The invention also relates to a glucose monitoring system comprising said flexible insert. Background technique [0003] Diabetes is one of the most common non-communicable diseases worldwide. It is the fourth or fifth leading cause of death in most developed countries, and there is substantial evidence of its prevalence in many developing and newly industrialized countries. Type 2 diabetes accounts for about 85 to 95% of all diabetes in developed countries and an even higher percentage in developing countries. To date, approximately 200 million people have been diagnosed with diabetes. The prevalence of the disease is expected to grow excessively in the upcoming years due to aging population and increasing number of overweight people. [0004] Complications of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/1455
CPCA61B5/0002A61B5/14507A61B5/1455A61B2560/0219A61B5/14532A61B2562/0233G02C7/04A61F9/0017A61B5/0031A61B5/6821A61B2562/12A61B2562/028H01L2224/16225
Inventor 威廉姆·贝斯林
Owner NXP BV
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