Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Method for measuring analyte concentration in a liquid sample

An analyte and concentration technology used in the field of measuring analyte concentration in liquid samples, which can solve problems such as expensive equipment and complex impedance technology

Inactive Publication Date: 2012-09-12
F HOFFMANN LA ROCHE & CO AG
View PDF4 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these issues can be addressed using impedance measurement techniques, impedance techniques typically require complex and expensive equipment

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for measuring analyte concentration in a liquid sample
  • Method for measuring analyte concentration in a liquid sample
  • Method for measuring analyte concentration in a liquid sample

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0026] For the purposes of promoting an understanding of the principles of the invention, reference will now be made to the embodiments illustrated in the drawings and specific language will be used to describe the same. It will however be understood that no limitation of the scope of the invention is intended. Any alterations and further modifications in the described embodiments and further applications of the principles of the invention as described herein will normally occur to those skilled in the art to which this invention pertains. An embodiment of the invention has been shown in great detail, however it will be obvious to a person skilled in the relevant art that some features which are not relevant to the invention may not be shown for the sake of clarity.

[0027] The body fluid analysis techniques and systems described herein address the problem of hematocrit interference when rapidly detecting analyte concentrations. This problem is solved by using the technique ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The blood glucose analysis technique and system described herein address the issue of hematocrit interference when rapidly detecting glucose concentrations. It addresses this issue by using a differential pulse voltammetry technique in which short high, frequency voltage pulses are applied to keep the diffusion layer within the reagent of the working electrode, and the pulses are applied in a limited voltage window (or range) that is below the peak, diffusion-limited current. The readings below the peak are then used to determine glucose concentrations. With this technique, glucose concentrations can be determined relatively fast (e.g., within 5 seconds) and independently of the hematocrit levels of the fluid being analyzed.

Description

Background technique [0001] Recently, there has been a tendency to monitor various health conditions by patients themselves. For example, diabetics traditionally monitor blood sugar levels multiple times a day. By its very nature, glucose monitoring requires a high degree of accuracy in the reported glucose values ​​with little or no interference from other substances contained in the sample. Other types of body fluid tests require similar characteristics. [0002] The most common techniques for measuring glucose levels in blood or interstitial fluid utilize electrochemical techniques. Electrochemical detection of glucose is typically based on the measurement of an electrical signal or property that is proportional to the analyte concentration. This signal is generated when a direct or indirect redox reaction occurs on the electrode surface or in its immediate vicinity. Some traditional electrochemical techniques include amperometry, coulometry and / or impedance measurement...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/487G01N33/49G01N27/48
CPCG01N27/3273G01N33/487G01N33/49G01N27/48
Inventor G.利卡
Owner F HOFFMANN LA ROCHE & CO AG
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products