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Oil or fat composition for prevention or treatment of depression or depressed conditions

An oil composition and a technology for depression, which are applied in the directions of drug combinations, medical preparations containing active ingredients, organic active ingredients, etc., can solve the problems that the curative effect cannot be accurately manifested, and achieve high safety, inhibition of disease incidence, improvement of effect of symptoms

Active Publication Date: 2012-08-29
THE NISSHIN OILLIO GRP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In general, antidepressants do not necessarily have a quick effect, and the curative effect cannot be shown exactly, so they must be taken continuously
However, since antidepressants have side effects, the balance between drug efficacy and side effects must be considered when taking them continuously

Method used

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  • Oil or fat composition for prevention or treatment of depression or depressed conditions
  • Oil or fat composition for prevention or treatment of depression or depressed conditions
  • Oil or fat composition for prevention or treatment of depression or depressed conditions

Examples

Experimental program
Comparison scheme
Effect test

manufacture example 1

[0039] Manufacturing method of test food 1

[0040] Add 7 parts by mass of MLCT (trade name: ヘルシオリセツタ, manufactured by Nissin Oyrio Group Co., Ltd., relative to the total amount of medium-chain fatty acids and long-chain fatty acids, the ratio of long-chain fatty acids: 87%, the content of fatty acids : M·LCT+MCT+LCT) was used as the oil and fat component in the feed, thereby obtaining the test food 1 containing 7% by mass of MLCT. The feed composition is shown in Table 1.

manufacture example 2

[0041] Manufacturing method of test food 2

[0042] Test food 2 containing 7 mass % of LCT was obtained by adding 7 parts by mass of LCT (trade name: Nissin Canoichira Oil, manufactured by Nissin Oilio Group Co., Ltd.) as an oil and fat component in the feed. The composition of the feed is shown in Table 1.

manufacture example 3

[0043] Manufacturing method of test food 3

[0044] Add 1 part by mass of MCT (trade name: ODO, manufactured by Nissin Oyrio Group Co., Ltd.) and 6 parts by mass of LCT (trade name: Nissin Oylio Group Co., Ltd. product) Thus, test food 3 containing 1% by mass of MCT and 6% by mass of LCT as fat and oil components in the feed was obtained. The composition of the feed is shown in Table 1. In addition, the ratio of the long-chain fatty acid to the total amount of the medium-chain fatty acid and long-chain fatty acid in this test food 3 was 86%.

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Abstract

Disclosed is an oil or fat composition characterized by containing a medium-chain fatty acid having 8 to 10 carbon atoms and a long-chain fatty acid having 12 to 24 carbon atoms both in the forms of triglycerides, wherein the content ratio of the long-chain fatty acid in the total amount of the medium-chain fatty acid and the long-chain fatty acid is 25 to 90 mass%. The composition is effective for the prevention or treatment of depression or depressed conditions, is highly safe, and causes no adverse side effect when ingested continuously.

Description

technical field [0001] The present invention relates to an oil composition for preventing or treating depression or a depressive state, in particular, to an oil composition for preventing or treating depression or a depressive state using medium-chain fatty acids and long-chain fatty acids in the form of triglycerides as active ingredients oil composition. Background technique [0002] Depression is an affective mental disorder (mood disorder), which is a mental illness characterized by depressed mood, restlessness and anxiety, decreased mental activity, decreased appetite, and insomnia. According to the statistics of the Japanese National Police Agency, in 2007, the number of suicides in Japan exceeded 30,000 for ten consecutive years. Most of the causes and motives were depression, so it is urgent to seek countermeasures. [0003] Antidepressants are clinically proven to be effective for depression. In general, antidepressants do not necessarily have a quick effect, and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/23A61K31/231A61K31/232A61P25/24
CPCA61K31/23A61K31/231A61K31/232A61P25/24
Inventor 筱原久美古川昭荣
Owner THE NISSHIN OILLIO GRP LTD
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