Novel multilayer co-extrusion medical transfusion film and preparation method thereof

Abstract

The invention relates to a novel multilayer co-extrusion medical transfusion film and a preparation method of the novel co-extrusion medical transfusion film. The materials of the novel multilayer co-extrusion medical transfusion film are divided into five layers in composition, wherein the first layer is an internal layer A and the ingredient of the internal A is polypropylene catalyzed by metallocene; the second layer is a bonding layer B and the ingredient of the bonding layer B is an ethylene-vinyl acetate copolymer; the third layer is a core layer C and the ingredient of the core layer C is mixed resin composed by random copolymerization polypropylene and an ethylene-alpha-octylene copolymer; the fourth layer is a bonding layer D and the ingredient of the bonding layer D is an ethylene-alpha-octylene copolymer; and the fifth layer is a weather-resistant layer E and the ingredient of the weather-resistant layer E is mixed resin composed by a random copolymerization polypropylene material, a styrene-ethylene-bivinyl rubber-styrene copolymer, and an ethylene-alpha-octylene copolymer. A multilayer co-extrusion technology is adopted in the preparation. The multilayer co-extrusion medical transfusion film provided by the invention has the advantages of high transparency, good weather-resistance and flexibility, wear resistance and the like, and is particularly appropriate for use as a packaging material in the field of medicine.

Description

technical field [0001] The invention relates to a film material used in medicine for packaging infusion, in particular to a multi-layer co-extruded medical infusion film and a manufacturing method thereof. Background technique [0002] At present, my country's medical infusion containers are mainly glass bottles. Although glass bottles have the advantages of high chemical stability, good transparency, and low price, they have disadvantages such as heavy weight, easy damage, high melting point, and inconvenient portability. This restricts the development space of glass infusion containers in large infusion products. [0003] In recent decades, the application of PVC as medical infusion bags, blood bags, and infusion tubes has become increasingly rapid. The advantages of PVC in medical equipment, such as transparency, flexibility, and low cost, have been widely recognized, but PVC still has fatal shortcomings as a packaging material for medical infusions: [0004] (1) In th...

AI Technical Summary

Problems solved by technology

The advantages of PVC in medical equipment, such as transparency, flexibility, and low cost, have been widely recognized, but PVC still has fatal shortcomings as a packaging material for medical infusions:

[0004] (1) In the process of preparing PVC medical infusion bags, in order to increase the flexibility of medical infusion bags, it is usually necessary to add more than 30% plasticizers to PVC, and the plasticizers used in PVC infusion packaging materials are mainly phthalates. Plasticizers such as formate esters are potentially carcinogenic. During the infusion process, the plasticizer will dissolve in the liquid medicine and inject the liquid into the human body, causing potential harm to the health of the patient.

[0005] (2) There will be a small amount of vinyl chloride monomer remaining in general PVC materials, and the toxic content of vinyl chloride monomer will bring certain harm to people's health

[0006] (3) For some drugs such as: oil-soluble vitamins, insulin, isosorbide dinitrate, chlorpromazine, etc., PVC infusion bags will produce certain drug adsorption, reducing the efficacy of drugs

[0007] (4) During the storage of PVC infusion bags, some liquid medicine will react with PVC, resulting in deterioration of the liquid medicine

[0008] (5) The post-treatment incineration process of PVC will produce toxic gas dioxins, which will cause great harm to the environment

However, the transparency of polyamide is poor, and fiber filaments will be produced during the production process, and the infusion process will enter the blood of the human body along with the liquid medicine, which will bring harm to people's health

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