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Sensing film for potassium ion-selective electrode, production method and application thereof

A technology of selecting electrodes and ion selectivity, which is applied in the direction of material analysis, instruments, and analysis materials through electromagnetic means, which can solve the problems of corrosion, harmfulness, and the adsorption of K ions on the damaged induction film, so as to achieve stable performance and improved Work efficiency, the effect of reducing the number of human hazards

Inactive Publication Date: 2012-07-11
上海中科润达医学检验实验室有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

This method needs to drop the membrane solution several times (10-15 times), and drop it again after the membrane solution is fully volatilized each time, which is time-consuming, laborious and harmful
And directly drop into the electrode chamber, most or all of the solute of the membrane solution is tetrahydrofuran, which can corrode all plastic products. Some additives in the plexiglass material in the electrode cavity will dissolve into the membrane solution, such as silicon-containing fillers, Destroy the sensing membrane to adsorb K ions, affecting the performance of the sensing membrane

Method used

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Embodiment 1~7

[0022] An inductive membrane for a potassium ion selective electrode, in which a solute and one or more solvents are uniformly mixed, and the solvent is volatilized to form a membrane;

[0023] The solute is composed of 20-40% polymer, 50-80% plasticizer, 2-10% ion-selective carrier and 0.1-2% fat-soluble salt, all calculated by weight percentage accounting for the total weight of the solute, the solute The total content of 150-400mg / ml;

[0024] The polymer is one or more of carboxyl polyvinyl chloride, high molecular weight polyvinyl chloride, or polyurethane;

[0025] The plasticizer is two-(2-ethylhexyl)decanedi;

[0026] The ion-selective carrier is valinomycin;

[0027] Described fat-soluble salt is potassium tetrakis (4-chlorophenyl) boric acid;

[0028] The solvent is tetrahydrofuran or a mixture of tetrahydrofuran and acetone.

[0029] The following are the concrete steps of the production method:

[0030] (1) Add the solvent to the solute mixture under a fume ho...

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Abstract

The invention provides a sensing film for a potassium ion-selective electrode, a production method and the application technical field thereof. Solute is evenly mixed with more or more solvents, and the film is formed after the solute is volatilized; the solute comprises 20 to 40 percents of polymers, 50 to 80 percent of plasticizers, 2 to 10 percent of ion-selective carriers and 0.1 to 2 percent liposoluble salt according to the weight percentage occupying the total weight of the solute; the total content of the solute is 150 to 400mg / ml; the polymers comprise one or more from carboxyl polyvinyl chloride, high molecular weight polyvinyl chloride and polyurethane; the plasticizers comprise di-(2-ethylhexyl) decanedi; the ion-selective carriers comprise valinomycin; the liposoluble salt is potassium tetra (4-chlorphenyl) boric acid; and the solvents comprise tetrahydrofuran or a mixture of the tetrahydrofuran and acetone.

Description

technical field [0001] The patent of the present invention relates to a potassium ion selective electrode sensing membrane, a production method and its application. Background technique [0002] The development of modern medicine, especially the rescue of clinical critically ill patients, needs to test the electrolytes of the human body, and the most important ion is potassium ion. Potassium is the main cation in cells, and its concentration is 150-160 mmol / L; while the concentration of potassium outside cells is only 3.5-5 mmol / L. Normal intracellular and intracellular potassium ion concentrations and concentration differences are closely related to some important functions of cells, including maintaining carbohydrate metabolism, glycogen storage, protein metabolism, intracellular osmotic pressure and acid-base balance, myocardial excitability and conductivity ; Maintain normal tension of skeletal muscle and nerve impulse conduction, and increase the tension of intestinal,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L27/22C08L27/06C08L75/04C08K5/35C08K5/11C08K5/55G01N27/333
Inventor 蒋丽敏刘作鹏王娜刘婵婵宋涛
Owner 上海中科润达医学检验实验室有限公司
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