Pyrazosulfuron effervescent tablet and preparation method thereof

A pyrazosulfuron-methyl effervescent tablet and a technology for pyrazosulfuron-methyl are applied in the field of agricultural herbicides and their preparation, which can solve problems such as harm to human health and environmental pollution, achieve less environmental pollution, reduce environmental pollution and facilitate recycling Effects of destruction or natural degradation

Inactive Publication Date: 2012-07-04
GUANGDONG ZHONGXUN AGRI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to develop a kind of environmental protection, high utilization rate, and easy-to-use pyrazosulfuron-methyl effervescent tablet in order to overcome the shortcomings of existing pesticide formulations such as environmental pollution and harm to human health

Method used

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  • Pyrazosulfuron effervescent tablet and preparation method thereof
  • Pyrazosulfuron effervescent tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1: 20% pyrazosulfuron-methyl effervescent tablet.

[0027] Weigh 20% of pyrazosulfuron-methyl original drug, 4% of wetting agent sodium lauryl sulfate, 3% of dispersant polycarboxylate, 4% of sodium lignosulfonate, 20% of disintegrant citric acid, disintegrate Agent sodium carbonate 20%, binder carboxymethyl cellulose 0.5%, excipient microcrystalline cellulose 20%, and the balance is filler. After sieving and mixing the above raw materials evenly, carry out wet or dry granulation, and dry after the granulation is completed; compress and sieve the granulated granules; after passing the inspection, 20% pyrazole can be obtained Sulfuron-methyl effervescent tablet.

[0028] This embodiment is used to control sedges and broad-leaved weeds in paddy fields, the dosage of active ingredients is 30-45 g / hectare, and the control effect is 85%-97%.

Embodiment 2

[0029] Example 2: 10% pyrazosulfuron-methyl effervescent tablet.

[0030] Weigh 10% of pyrazosulfuron-methyl original drug, 3% of wetting agent fatty alcohol polyoxyethylene ether, 4% of dispersing agent polycarboxylate, 4% of lignin, 20% of disintegrating agent citric acid, disintegrating agent sodium carbonate 20%, binder carboxymethyl cellulose 0.5%, excipient microcrystalline cellulose 28.5%, and the balance is filler. After sieving and mixing the above raw materials evenly, carry out wet or dry granulation, and dry after the granulation is completed; compress and sieve the granulated granules; after passing the inspection, 10% pyrazole can be obtained Sulfuron-methyl effervescent tablet.

[0031] This embodiment is used to control sedges and broad-leaved weeds in paddy fields, the dosage of active ingredients is 30-45 g / hectare, and the control effect is 85%-95%.

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Abstract

The invention relates to a pyrazosulfuron effervescent tablet and a preparation method thereof, and the pyrazosulfuron effervescent tablet comprises the following components by weight: 0.5-20% of pyrazosulfuron, 1-5% of wetting agents, 5-10% of dispersants, 20-50% of disintegrating agents, 0.5-4% of binders, 5-40% of excipients, and the balance of fillers. The preparation method comprises the following steps: screening raw materials, well mixing to obtain a mixture; performing wet-method or dry-method granulation of the mixture; drying after the granulation is completed; tabletting and screening the granulated granules; performing analysis and examination to obtain the pyrazosulfuron effervescent tablet. The invention overcomes the disadvantages of suspending agents and wettable powder, and has the advantages of both environmental protection and low using cost; the invention reduces environment pollution, and reduces peasant labor intensity and environment pollution caused during drug administration.

Description

technical field [0001] The invention relates to an agricultural herbicide and a preparation method thereof, in particular to a pyrazosulfuron-methyl effervescent tablet and a preparation method thereof. Background technique [0002] Pyrazosulfuron-methyl, a sulfonylurea herbicide, can effectively inhibit the formation of acetolactate synthase. It can control sedges and broad-leaved weeds such as duck tongue grass, pig yanglings, three-edge grass, water peanuts, etc. in paddy fields. [0003] At present, pyrazosulfuron-methyl is generally made into wettable powder in use. Although wettable powder has low production cost, it is not environmentally friendly, and the dust drift is relatively serious, which brings inconvenience to production, transportation and use. [0004] Effervescent tablet is a new type of dosage form. In recent years, scientific research institutes and enterprises at home and abroad have paid more attention to the research of this type of dosage form. Ef...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N47/36A01N25/34A01P13/00
Inventor 阎工程周斌彭述明
Owner GUANGDONG ZHONGXUN AGRI TECH
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