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Method for preparing compound ginseng preparation and antioxidation activity of compound ginseng preparation

A technology of anti-oxidation and ginseng, which is applied in the research and development field of its own pharmaceutical products, and can solve the problems of antioxidant toxicity and carcinogenicity

Inactive Publication Date: 2012-06-27
SHANDONG UNIV AT WEIHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, synthetic antioxidants have certain toxicity and carcinogenic effects.

Method used

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  • Method for preparing compound ginseng preparation and antioxidation activity of compound ginseng preparation
  • Method for preparing compound ginseng preparation and antioxidation activity of compound ginseng preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1. a preparation method of compound ginseng preparation with antioxidant effect, is characterized in that comprising following process:

[0018] (1) The weight ratio of raw materials is: ginseng 9g, Codonopsis 6g, Porphyridium 10g;

[0019] (2) Put ginseng and Codonopsis ginseng into 8 times the amount of 70% ethanol to extract 8 times at room temperature, then seal and sonicate for 30 minutes at a temperature of 30°C and a power of 80W, then filter with gauze, and use 6 times and 4 times the amount of filter residues respectively Repeat the extraction with 70% ethanol once, filter to obtain the filtrate;

[0020] (3) The filtrate in (2) is merged, reclaims ethanol, obtains Radix Ginseng, Radix Codonopsis extract;

[0021] (4) Centrifuge Porphyridium algae with a 5000r / min centrifuge for 10min, then suspend it in pH 7.4, 50mmol / L phosphate buffer, perform ultrasonic crushing, break for 5s, interval 5s, 20 times, use 10000r / min high speed Centrifuge in a refrigerated c...

Embodiment 2

[0025] 1. a preparation method of compound ginseng preparation with antioxidant effect, is characterized in that comprising following process:

[0026] (1) The weight ratio of raw materials is: ginseng 12g, Codonopsis 9g, Porphyridium 20g;

[0027] (2) Add 10 times the amount of ginseng and Codonopsis pilosula to 70% ethanol at room temperature and extract for 10 hours, then seal and sonicate for 30 minutes at a temperature of 30°C and a power of 80W, then filter with gauze, and use 6 times and 4 times the amount of filter residues respectively Repeat the extraction with 70% ethanol once, filter to obtain the filtrate;

[0028] (3) The filtrate in (2) is merged, reclaims ethanol, obtains Radix Ginseng, Radix Codonopsis extract;

[0029] (4) Centrifuge Porphyridium algae with a 5000r / min centrifuge for 10min, then suspend it in pH 7.4, 50mmol / L phosphate buffer, perform ultrasonic crushing, break for 5s, interval 5s, 20 times, use 10000r / min high speed Centrifuge in a refrige...

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Abstract

The invention belongs to the technical field of the research and development of medicine products, and relates to a method for preparing a compound ginseng preparation and the antioxidation activity of the compound ginseng preparation. The method comprises the following steps of: adding 70 percent ethanol into ginseng and szechuan tangshen root, leaching at room temperature, performing ultrasound at the temperature of 30 DEG C under the condition of power of 80 W for 30 minutes, filtering, extracting filter residues once again by using 70 percent ethanol in an amount 6 times and 4 times that of the filter residues respectively, and filtering to obtain filtrate; mixing the filtrate, and recovering the ethanol to obtain a ginseng and szechuan tangshen root extract; centrifuging porphyridium cruentum by using a centrifugal machine of which the rotation speed is 5,000 revolutions / minute for 10 minutes, suspending in phosphate buffer of which the concentration is 50 mmol / L and the pH value is 7.4, performing ultrasonication, centrifuging by using a high-speed freezing centrifugal machine to obtain supernate, and freezing and drying to obtain a dry substance; and mixing the dry substance and the ginseng and szechuan tangshen root extract uniformly to obtain the compound ginseng preparation. The compound ginseng preparation has an antioxidation effect.

Description

technical field [0001] The invention belongs to the technical field of research and development of pharmaceutical products. The invention relates to a preparation method of a compound ginseng preparation and its antioxidant activity. Background technique [0002] Ginseng Panax ginseng C.A.Mey. is the root of Araliaceae plant ginseng, flat in nature, sweet in taste, slightly bitter, and slightly warm. Return spleen, lung meridian. Greatly invigorate vital energy, restore pulse and solidify, invigorate the spleen and lungs, promote body fluid and quench thirst, soothe the nerves and improve intelligence. Mainly contains ginsenosides, also contains organic acids and esters, vitamins, sterols, adenosine invertase, L-aspartase, β-amylase, sucrose invertase; maltol, kaempferol, ginsenosides And copper, zinc, iron, manganese and more than 20 kinds of trace elements. Ginseng can regulate the balance between the excitatory process and the inhibitory process of the central nervous...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/344A61P39/06
Inventor 张崇禧张成城侯欣池郑友兰
Owner SHANDONG UNIV AT WEIHAI
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