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Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method and application thereof

A technology for cardiovascular and cerebrovascular diseases and a composition is applied in the field of traditional Chinese medicine compositions, which can solve the problems of multiple adverse reactions, toxic accumulation, easy recurrence and the like, and achieve the effect of good therapeutic effect.

Inactive Publication Date: 2012-05-23
HUNAN JIUDIAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although the currently marketed Western medicines for treating cardiovascular and cerebrovascular diseases, such as cilostazol, have good curative effects, there are many adverse reactions, and they are prone to relapse after drug withdrawal, and most patients with cardiovascular and cerebrovascular diseases need to take medicine for a long time. There is a hidden danger of toxic accumulation in the body of similar drugs, which may cause greater harm, so most patients are more willing to take pure Chinese medicine preparations with definite curative effect and good safety. A traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases. The medicine is mainly composed of pure Chinese medicinal materials such as Polygonum cuspidatum, alum and honeysuckle, and has outstanding curative effects especially in the treatment of hyperlipidemia and arteriosclerosis

Method used

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  • Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method and application thereof
  • Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method and application thereof
  • Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method and application thereof

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Effect test

Embodiment l

[0074] Embodiment 1: tablet of the present invention

[0075] Take by weighing Polygonum cuspidatum 500g, Alum 60g, Flos Lonicerae 300g, Radix Scrophulariae 300g, Angelica 200g, Rhubarb 100g, Radix Astragali 400g and Radix Glycyrrhizae 200g respectively, prepare the tablet of the present invention according to the following method:

[0076] Grind the weighed Polygonum cuspidatum, rhubarb and angelica, add 60% ethanol to soak for 10 minutes, reflux extraction twice, add 10 times the amount of ethanol for the first time, extract for 2 hours; add 5 times the amount of ethanol for the second time, extract for 0.5 hours; Combine the extracts, recover ethanol, concentrate to a relative density of 1.2 (65°C), and set aside; then soak the weighed honeysuckle, scrophulariae, astragalus and licorice in water for 30 minutes, decoct 3 times, add 8 times each time Extract with water for 1 hour; combine the decoction and concentrate to a relative density of 1.2 (65°C); The above-mentioned ...

Embodiment 2

[0077] Embodiment 2, tablet of the present invention

[0078] Take respectively 800g of Polygonum cuspidatum, 80g of alum, 200g of honeysuckle, 400 parts of Radix Scrophulariae, 100g of Angelica sinensis and 200g of rhubarb, and prepare the tablet of the present invention according to the following method:

[0079] Grind the weighed Polygonum cuspidatum, rhubarb and angelica, add 75% ethanol to soak for 60 minutes, reflux extraction once, add 8 times the amount of alcohol, extract for 1.5 hours, recover the ethanol, concentrate for later use; then weigh the honeysuckle, Scrophulariaceae, Soak astragalus and licorice in water for 60 minutes, decoct twice, add 10 times the amount of water to extract for 2 hours for the first time, and extract for 0.5 hours for the second time with 5 times the amount of water; Alcohol, concentrated and combined with the above-mentioned alcohol concentrated solution, dried in vacuum, mixed with alum and pulverized into fine powder, then added appr...

Embodiment 3

[0080] Embodiment 3: tablet of the present invention

[0081] Weigh 990g of Polygonum cuspidatum, 100g of alum, and 500g of honeysuckle, crush Polygonum cuspidatum and add 70% ethanol to soak for 0.5 hours, reflux extraction 3 times, each time add 8 times of alcohol to extract for 1.5 hours, combine the extracts, recover ethanol, concentrate , vacuum-dried, added alum and mixed evenly and pulverized into fine powder, then added an appropriate amount of tablet auxiliaries such as microcrystalline cellulose, magnesium stearate and starch, and prepared by a common tablet preparation method to obtain 1000 tablets of the present invention.

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Abstract

The invention provides a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases, which is mainly prepared from bulk pharmaceuticals such as giant knotweed, white vitriol, honeysuckle flower and like with a medicinal excipient in a certain weight ratio. The Chinese medicinal composition can be prepared into a dosage form of any conventional oral preparation. The Chinese medicinal composition has the effects of clearing away heat and toxic materials, activating blood, dredging collaterals, lowering lipid and removing ecchymoses. As proved by clinical observation, the Chinese medicinal composition can be used for regulating blood fat and treating a plurality of cardiovascular and cerebrovascular diseases, and has a good treatment effect on the formation of hyperlipidemia incorporated artery atheromatous plaques.

Description

field of invention [0001] The invention relates to a traditional Chinese medicine composition, which is used for treating cardiovascular and cerebrovascular diseases, and is especially suitable for treating hyperlipidemia and arteriosclerosis, and belongs to the field of traditional Chinese medicines. Background technique [0002] Cardiovascular and cerebrovascular diseases are one of the common clinical syndromes, with various clinical manifestations, such as coronary heart disease, atherosclerosis, hyperlipidemia, hypertensive heart disease, etc. With the extension of people's average life expectancy, my country is gradually entering an aging society, and the morbidity and mortality of cardiovascular and cerebrovascular diseases are also increasing year by year. This not only seriously affects personal health and quality of life, but also affects the family, the country and society has brought an extremely heavy economic and spiritual burden. Therefore, the treatment of ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/808A61P3/06A61P9/10A61K33/06
Inventor 朱志宏程丑夫卜振军杨静
Owner HUNAN JIUDIAN PHARMA
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