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Preparation method of calamine lotion

A technology of calamine lotion and preparation method, which is applied in the field of pharmaceutical products, and can solve problems such as fast sedimentation of finished products, uneven packaging of finished products, and affecting product quality, so as to save time, improve drug efficacy, and layer settlement slow effect

Inactive Publication Date: 2012-03-21
殷峰林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The amount prepared by this method is small, and the finished product settles quickly, which brings a lot of troubles to the packaging. It needs to be stirred while filling. A little carelessness can lead to uneven packaging and affect product quality.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] In a stainless steel container with a capacity of 500 liters, first add distilled water accounting for 75% of the total volume, then raise the temperature to 40°C, add 0.01% of the total amount of surfactant polysorbate, 0.01% of bromogeramine, and then add 5% glycerin, stir evenly; Pack into account for total amount 1.6% calamine powder and 0.6% zinc oxide powder with nylon plastic net bag, wash in the above solution in stages, (nylon plastic net bag density is 3# sieve mesh); Then add the remaining distilled water and stir vigorously; send the product into the disinfection box for disinfection, and then pack it to obtain the finished product

Embodiment 2

[0014] In a stainless steel container with a capacity of 500 liters, first add distilled water accounting for 75% of the total volume, then raise the temperature to 45°C, add 0.01% of the total amount of surfactant polysorbate, 0.01% of bromogeramine, and then add 5% glycerin, stir evenly; Pack into account for total amount 1.6% calamine powder and 0.6% zinc oxide powder with nylon plastic net bag, wash in the above solution in stages, (nylon plastic net bag density is 3# sieve mesh); Then add the remaining distilled water and stir vigorously; send the product into the disinfection box for disinfection, and then pack it to obtain the finished product

Embodiment 3

[0016] In a stainless steel container with a capacity of 500 liters, first add distilled water accounting for 75% of the total volume, then raise the temperature to 50°C, add 0.01% of the total amount of surfactant polysorbate, 0.01% of bromogeramine, and then add 5% glycerin, stir evenly; Pack into account for total amount 1.6% calamine powder and 0.6% zinc oxide powder with nylon plastic net bag, wash in the above solution in stages, (nylon plastic net bag density is 3# sieve mesh); Then add the remaining distilled water, stir vigorously evenly; send the product into the disinfection box for disinfection, and pack it separately to obtain the finished product after disinfection.

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PUM

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Abstract

The invention discloses a preparation method of a calamine lotion, and the product belongs to the field of pharmacy. The calamine lotion is the over the counter drug of dermatological pharmacy, is the light pink injectable suspension in appearance, is precipitated after being placed, but is the uniform injectable suspension after being shaken out. Calamine and zinc oxide which are contained in the product have the constriction and protection effects, and also have weaker antiseptic function, so the calamine lotion can be applied in acute pruritus skin diseases and various rashes, such as urticaria, prickly heat, eczema and the like. The product is produced from the raw materials of: calamine powder, zinc oxide powder, glycerol, polysorbate, bromogeramine and distilled water. The calamine lotion which is prepared by the method is fine, has low layered sedimentation velocity, is not easy to block after long-term storage, and is the calamine lotion with good quality.

Description

Technical field: [0001] The product of the invention belongs to the pharmaceutical field, and is characterized in that it relates to a preparation method of calamine lotion. Background technique: [0002] Calamine lotion is an over-the-counter drug for dermatology. It is a pale pink suspension that can settle after standing, but it should become a uniform suspension after shaking. Calamine and zinc oxide contained in this product have astringent and protective effects, and also have weak antiseptic effects. They can be used for acute itching skin diseases and various rashes, such as urticaria, prickly heat, and eczema. This product is for external use and cannot be taken orally. It should avoid contact with eyes and other mucous membranes. It is not very irritating to intact skin. It may cause short-term mild pain after medication, and generally does not cause severe pain. If the skin of the affected area is damaged or seeps , it may cause obvious pain, so it is not suitabl...

Claims

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Application Information

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IPC IPC(8): A61K33/30A61K9/00A61P17/04A61P17/00
Inventor 殷峰林
Owner 殷峰林
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