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Compound Chinese medicinal preparation for treating depression and preparation method thereof

A depression and preparation technology, applied in the field of traditional Chinese medicine preparations, can solve the problems of slow onset of depression, large dependence, and large side effects.

Inactive Publication Date: 2012-03-14
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, Western medicine has the disadvantages of slow onset of effect, large side effects, low safety factor, and large dependence in the treatment of depression.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] A compound traditional Chinese medicine preparation for treating depression, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum 8, Radix Paeoniae Alba 8, Poria cocos 10, Angelica 8, Pinellia 10, Magnolia officinalis 8, Shichangpu 8, Curcuma 8, Keel 13, oyster 13, licorice 5.

[0012] The preparation method is to wash the above 11 medicinal materials, mix them in proportion, add 6 times the total weight of the medicinal materials and decoct them for 3 times, each time for 50 minutes, combine the decoctions for 3 times, filter, and concentrate to obtain 60°C It is a liquid extract with a specific gravity of 1.17.

Embodiment 2

[0014] A compound traditional Chinese medicine preparation for treating depression, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum 10, Radix Paeoniae Alba 10, Poria cocos 12, Angelica 10, Pinellia 12, Magnolia officinalis 10, Shichangpu 10, Curcuma 10, Keel 15, oyster 15, licorice 6.

[0015] All the other are with embodiment 1.

Embodiment 3

[0017] A compound traditional Chinese medicine preparation for treating depression, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum 12, Radix Paeoniae Alba 12, Poria 14, Angelica 12, Pinellia 14, Magnolia officinalis 12, Shichangpu 12, Curcuma 12, Keel 17, oyster 17, licorice 7.

[0018] The preparation method is to wash the above 11 medicinal materials, mix them in proportion, add 6 times the total weight of the medicinal materials, and decoct 3 times in ethanol with a volume ratio of 70%, 50 minutes each time, combine the decoction liquid for 3 times, filter, and Concentrate to obtain a liquid extract with a specific gravity of 1.17 at 60°C.

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PUM

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Abstract

The invention relates to a compound Chinese medicinal preparation for treating depression. The compound Chinese medicinal preparation comprises the following Chinese medicinal raw materials in weight by percentage: 8-12 percent of root of Chinese thorowax, 8-12 percent of white paeony root, 10-14 percent of tuckahoe, 8-12 percent of angelica, 10-14 percent of pinellia ternate, 8-12 percent of officinal magnolia bark, 8-12 percent of acorus gramineus, 8-12 percent of turmeric root tuber, 13-17 percent of dragon bone, 13-17 percent of oyster and 5-7 percent of liquoric root. A preparation method of the compound Chinese medicinal preparation comprises the following steps of: cleaning the 11 medicinal materials; mixing in proportion; adding water in an amount which is 6-8 times the total weight of the medicinal materials or ethanol in an amount which is 70 percent of the volume ratio to decoct for 3 times, 50 minutes each time; combining decoction for 3 times; filtering; and concentrating to obtain liquid extract with specific gravity of 1.17 at the temperature of 60 DEG C. By adopting the conventional reparation process, the preparation can be prepared into any one pharmaceutically said formulation, such as tablets, capsules, granules, oral liquid, pills and syrup. The compound Chinese medicinal preparation for treating the depression prepared by the invention has the advantages of obvious curative effect, quick response and no adverse effect, and is suitable to be clinically applied and promoted.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating depression and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] Depression is mainly manifested as significant and persistent depression, loss of interest, slow thinking, pessimism and hopelessness, lack of initiative, self-blame, poor diet, sleep disturbance, paranoia, often accompanied by multi-system and objective examination of the whole body Inconsistent with a variety of physical discomfort, severe cases may appear suicidal thoughts and behaviors. According to statistics, depression has ranked second in the burden of disease in China. It is estimated that in 2020, depression will become the second largest disease after cardiovascular disease, about 80% of patients will relapse, and 10%-15% of patients will eventually commit suicide, which can occur in all ages and has become a c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/9066A61P25/24A61K35/02A61K35/56A61K35/618
Inventor 吕爱平郑光吕诚姜淼赵宁
Owner INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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