Preparation method of Jiangzhiling tablets

A technology for reducing lipids and preparing Polygonum multiflorum, which is applied in the directions of medical preparations, pharmaceutical formulations, and plant raw materials containing active ingredients, can solve the problems of easy loss of heat-sensitive ingredients, low recovery rate of active ingredients, and troublesome post-processing, and shorten production. The effect of cycle time, good clarity and improved extraction efficiency

Active Publication Date: 2013-08-21
TAIJI GRP CHONGQING FULING PHARM FACTORY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The decoction method and reflux method are used to extract the active ingredients of the prescription medicinal materials in the above methods, which have disadvantages such as cumbersome process, long extraction time, high extraction temperature, high energy consumption, easy loss of heat-sensitive ingredients, low recovery rate of active ingredients, troublesome post-processing, etc.

Method used

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  • Preparation method of Jiangzhiling tablets

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Prescription: Polygonum multiflorum 6.66kg, Lycium barbarum 6.66kg, Polygonatum 8.88kg, Hawthorn 5.64kg, Cassia 1.32kg

[0034] The preparation method comprises the following steps:

[0035] a. Extraction of Polygonatum and Lycium barbarum

[0036] a1. Mix the prescribed amount of Rhizoma Polygonatum and Fructus Lycium barbarum, crush it into a coarse powder, and set aside;

[0037] a2. Add water equivalent to 7 times the total weight of sealwort and medlar into the batching tank, heat to 65°C and keep warm; switch the three-way valve to the position of the batching tank, turn on the agitator, diaphragm pump and diaphragm filter press of the batching tank, Pump the water in the batching tank into the membrane filter press (using 80±10 L / m 2 .s polypropylene multifilament filter cloth), when the press filtrate flows back into the batching tank, add the medicinal powder obtained in step a1 into the batching tank at a constant speed, after the addition is completed, 6...

Embodiment 2

[0045] Prescription: Polygonum multiflorum 6.66kg, Lycium barbarum 6.66kg, Polygonatum 8.88kg, Hawthorn 5.64kg, Cassia 1.32kg

[0046] The preparation method comprises the following steps:

[0047] a. Extraction of Polygonatum and Lycium barbarum

[0048] a1. Mix the prescribed amount of Rhizoma Polygonatum and Fructus Lycium barbarum, crush it into a coarse powder, and set aside;

[0049] a2. Add water equivalent to 6 times the total weight of sealwort and medlar into the batching tank, heat to 55°C and keep warm; switch the three-way valve to the position of the batching tank, turn on the agitator, diaphragm pump and diaphragm filter press of the batching tank, Pump the water in the batching tank into the membrane filter press (using 80±10 L / m 2 .s polypropylene multifilament filter cloth), when the press filtrate flows back into the batching tank, add the powder obtained in step a1 into the batching tank at a constant speed, after the addition is completed, the membran...

Embodiment 3

[0057] Prescription: Polygonum multiflorum 6.66kg, Lycium barbarum 6.66kg, Polygonatum 8.88kg, Hawthorn 5.64kg, Cassia 1.32kg

[0058] The preparation method comprises the following steps:

[0059] a. Extraction of Polygonatum and Lycium barbarum

[0060] a1. Mix the prescribed amount of Rhizoma Polygonatum and Fructus Lycium barbarum, crush it into a coarse powder, and set aside;

[0061] a2. Add water equivalent to 8 times the total weight of sealwort and medlar into the batching tank, heat to 60°C and keep warm; switch the three-way valve to the position of the batching tank, turn on the agitator, diaphragm pump and diaphragm filter press of the batching tank, Pump the water in the batching tank into the membrane filter press (using 80±10 L / m 2.s polypropylene multifilament filter cloth), when the press filtrate flows back into the batching tank, add the powder obtained in step a1 into the batching tank at a constant speed, after the addition, 60 ° C diaphragm filter p...

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Abstract

The invention discloses a preparation method of Jiangzhiling tablets. The method employs the technology of integrated membrane filter pressing circulating extraction and separation to replace present decocting method and reflux method to extract the effective ingredients of prescribed medicinal materials. With the method of the invention, the technological process is simplified, the production period is greatly shortened, and the energy consumption is saved, thus benefiting for environmental protection and waste residue utilization. Besides, the method provided in the invention can reduce theconsumption of the extraction solvent ethanol and substantially enhance the recovery rate of effective ingredients.

Description

technical field [0001] The invention belongs to the field of pharmacy and relates to a preparation method of a traditional Chinese medicine preparation. Background technique [0002] The Chinese Pharmacopoeia 2010 Edition records: Jiangzhiling Tablet has the effects of nourishing the liver and kidney, nourishing blood and improving eyesight. It is clinically used for hyperlipidemia with liver and kidney deficiency. Symptoms include dizziness, dizziness, and premature graying of beard and hair. The prescription is 222g of Radix Polygoni Multiflori, 222g of Fructus Lycii, 296g of Polygonatum, 148g of Hawthorn, and 44g of Semen Cassiae. The preparation method is to decoct sealwort and medlar with water twice, the first time for 2 hours, the second time for 1 hour, filter, the filtrate is concentrated into a thick paste, and set aside; the rest are made of Polygonum multiflorum and other three flavors, heated and refluxed with 50% ethanol Extract twice, each time for 1 hour, fi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P3/06
Inventor 冯天炯朱久武殷树荣彭爱国喻贵英
Owner TAIJI GRP CHONGQING FULING PHARM FACTORY CO LTD
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