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Preparation technique and application of eye protection plaster

A protective sticker, gel layer technology, applied in ophthalmic treatment, medical science, dressings, etc., can solve the problems of closed eyes of patients and weak protection from direct damage to the eyes, so as to protect the direct damage, protect the eyes, and prevent exposed corneas. inflammation effect

Active Publication Date: 2014-08-13
HANGZHOU JUJIU SCI & BIOTECHNOLOGY CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the patient's eyes cannot be closed, because the film of the transparent part of the product is relatively thin, and the protective effect on direct eye damage is relatively weak; experts from the Department of Anesthesiology at Boston Medical Center in the United States and some ophthalmology experts in my country believe that it is necessary to prevent exposure of patients under general anesthesia. For keratitis or direct damage to the eye, the best way is to close the eye and maintain the local physiological environment of the eye

Method used

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  • Preparation technique and application of eye protection plaster
  • Preparation technique and application of eye protection plaster

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take 4% cross-linked sodium polyacrylate, 1.5% CMC, 0.3% aluminum glycylate, 0.2% EDTA, 0.1% paraben according to the proportion of the formula, and disperse the above ingredients in 15 % glycerin and mix well to obtain liquid A.

[0027] Take 0.15% tartaric acid and 0.02% K-90 according to the proportion of the formula, and dissolve them in an appropriate amount of deionized water in turn under the stirring state of 200-1000rpm, spread 3% carbomer evenly on the liquid surface, and let it stand for swelling After 12 to 24 hours, after stirring evenly, add an aqueous solution containing 1% polyvinyl alcohol, and mix evenly to obtain liquid B.

[0028] Add the pre-configured liquid A to the liquid B under stirring at 15-60rpm to form a gel matrix, adjust the pH value to 7.0 with triethanolamine or NAOH, and add deionized water to the required content. Continue stirring and mixing, apply the gel matrix on the coating machine, cut, and then harden to obtain the gel layer a...

Embodiment 2

[0030] Take 8.5% sodium polyacrylate, 0.03% aluminum glycylate and 0.02% EDTA, 0.5% paraben, 5% titanium dioxide according to the proportion of the formula, and the above ingredients are dispersed in 30% moisturizing agent in turn under the stirring state of 15-60rpm and mix well to obtain liquid A.

[0031] Take 0.1% tartaric acid and 0.01% k-90 according to the proportion of the formula, and dissolve them in an appropriate amount of deionized water in turn under the stirring state of 200-1000rpm, spread 0.4% carbomer evenly on the liquid surface, and let it stand for swelling After 12 to 24 hours, after stirring evenly, add an aqueous solution containing 0.1% polyvinyl alcohol and mix evenly to obtain liquid B.

[0032] Add the pre-configured liquid A to the liquid B under stirring at 15-60rpm to form a gel matrix, adjust the pH value to 6.5 with triethanolamine or NAOH, and add deionized water to the required content. Continue stirring and mixing, apply the gel matrix on t...

Embodiment 3

[0034] Take 6% partially cross-linked sodium polyacrylate, 1% CMC, 0.3% aluminum glycylate and 0.3% EDTA, 0.5% paraben, 2% titanium dioxide according to the proportion of the formula, and mix the above ingredients in turn at a speed of 15-60rpm Disperse in 20% humectant and mix well to obtain liquid A.

[0035] Take 0.4% tartaric acid and 0.01% K-90 according to the proportion of the formula, and dissolve them in an appropriate amount of deionized water in turn under the stirring state of 200-1000rpm, spread 2% carbomer evenly on the liquid surface, and let it stand for swelling After 12 to 24 hours, after stirring evenly, add an aqueous solution containing 0.5% polyvinyl alcohol, and mix evenly to obtain liquid B.

[0036]Add the pre-configured liquid A to the liquid B under stirring at 15-60rpm to form a gel matrix, adjust the pH value to 6.5-8.0 with triethanolamine or NAOH, and make up to the required amount of deionized water content, continue to stir and mix, apply the ...

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Abstract

The invention relates to an eye protection plaster which is composed of a supporting layer, a gel layer and an isolating layer. The preparation technique comprises the following steps: evenly mixing and dispersing 4-8.5% of polyacrylic acid polymer, 0-1.5% of CMC (carboxymethyl cellulose), 0.03-0.3% of crosslinking agent, 0.02-0.3% of crosslinking regulator, 0-1% of bacteriostat and 0-5% of filler in 5-30% of humectant to obtain a solution A; evenly dispersing 0.1-0.4% of tartaric acid and 0.01-0.08% of polyvinylpyrrolidone in a proper amount of deionized water, spreading 0.4-3% of carbomer on the liquid surface, standing to swell for 12-24 hours, adding 0.1-1% of polyvinyl alcohol into a proper amount of water, dissolving by heating, and evenly mixing with the previous solution to obtain a solution B; and dispersing the solution A in the solution B to form a gel substrate, regulating the pH value to 6.5-8.0, adding deionized water to 100%, evenly mixing, coating, cutting, hardening and packaging to obtain the finished product. The eye protection plaster is used for protecting eyes of general anesthesia patients and patients in deep coma.

Description

technical field [0001] The invention relates to an eye protection patch, in particular to a surgical eye protection which is applied to patients undergoing general anesthesia and deep coma to prevent and control the occurrence of exposure keratitis, and to prevent and protect the patient's eyes from being damaged by foreign objects. paste. Background technique [0002] In our country, tens of thousands of patients need general anesthesia for various reasons every year. The patient is injected with various anesthetics and muscle relaxants. After deep anesthesia, the patient does not feel pain and the muscles relax. Although this situation is conducive to the operation, it also relaxes the muscles of the patient's eyelids and keeps the eyes open. . [0003] The common sense of daily life tells us that under normal conditions, the eyes will blink continuously, the frequency is about 15 times per minute, and the purpose is to keep the cornea moist. For patients under general ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F13/02A61F9/00A61L15/00C08L33/02C08K13/02
Inventor 舒朝锋俞瑞珺
Owner HANGZHOU JUJIU SCI & BIOTECHNOLOGY CO
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