Multi-degree-of-freedom electric microinjector

Abstract

The invention provides a multi-degree-of-freedom electric micro-injection instrument. In the multi-degree-of-freedom electric micro-injection instrument, an X-axis direction sliding rail is arranged on a pedestal; an X-axis direction translation platform is arranged on the X-axis direction sliding rail; a micrometer head knob is arranged on one side of the X-axis direction translation platform; aY-axis direction sliding rail is arranged on the X-axis direction translation platform; a Y-axis direction translation platform is arranged on the Y-axis direction sliding rail; a micrometer head knob is arranged on one side of the Y-axis direction translation platform; a Z-axis direction sliding block sleeve is arranged on the Y-axis direction translation platform; a micrometer head knob is arranged on the top of the sleeve and is connected with a Z-axis direction sliding block in the sleeve; the middle part of the sleeve is provided with an opening through which a substrate is connected with the Z-axis direction sliding block; a connecting plate is arranged on the bottom side of the substrate and is connected with the Z-axis direction sliding block through a pitch adjusting nut; a microinjector and a motor are arranged on the substrate; one end of a screw rod is connected with a needle core of the microinjector; and the other end of the screw rod is connected with the output end of the motor. The multi-degree-of-freedom electric micro-injection instrument has a simple structure and the effects of stable and high-precision needle tip positioning and slow controlled injection.

Description

technical field [0001] The invention relates to a medical microinjector, in particular to a multi-degree-of-freedom electric microinjector for drug delivery to the subretinal cavity under a microscope. Background technique [0002] As we all know, retinal detachment, diabetic retinopathy, retinal vein occlusion and other fundus diseases can seriously affect vision and even lead to blindness. At present, a large amount of research work on these diseases is being widely carried out in animal experiments (such as rats, mice, etc.) to explore the disease mechanism and observe the efficacy of new treatment methods. At present, the subretinal space is considered to be a relatively immune-privileged area, and the need for the application of subretinal injection technology is increasing, especially for gene transfection to retinal cells. However, it is very difficult to master the subretinal injection technique proficiently. Under the microscope, the accidental and uncontrollable s...

AI Technical Summary

Problems solved by technology

Since the requirement for intraocular injection is to make a scleral tunnel puncture under the operating microscope, the degree of freedom needs to be changed at any time, instead of simply piercing the sclera and choroid directly, so it is difficult to match it with a stereotaxic instrument / intracellular injection instrument

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