Application of cimetidine in preparation of medicine for treating epidermis to papillary dermis trauma

A technology of cimetidine and dermal papilla, applied in the field of application of cimetidine in the preparation of medicaments for treating wounds from the epidermis to the dermal papilla

Inactive Publication Date: 2011-12-21
GUILIN UNIV OF ELECTRONIC TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the application of cimetidine in the treatment of epidermis to dermis papillary wound has not been reported yet.

Method used

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  • Application of cimetidine in preparation of medicine for treating epidermis to papillary dermis trauma
  • Application of cimetidine in preparation of medicine for treating epidermis to papillary dermis trauma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Cimetidine produced by Jiangmen Hengjian Pharmaceutical Co., Ltd., batch number: 081002, was used in the treatment of wounds from the epidermis to the papillary dermis. When in use, after debridement of the surface wound, sprinkle cimetidine powder on the wound surface, the dosage is based on 0.2g cimetidine powder for 1cm2 wound surface, the maximum amount is not more than 0.8g, 2-3 times a day .

Embodiment 2

[0042] The cimetidine produced by Jiangmen Hengjian Pharmaceutical Co., Ltd., batch number: 081001, was prepared according to the ratio of cimetidine 0.1g plus normal saline 1ml, mixed evenly, put into a medicine bottle, sealed, and sterilized. When using the product, debride the surface wound first, then scrub the wound surface with liquid medicine, the dosage is 2ml liquid medicine for 1cm2 wound surface, 2-3 times a day.

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Abstract

The invention discloses an application of cimetidine in the preparation of a medicine for treating wounds from the epidermis to the papillary dermis. According to the results of animal experiments and clinical trials, it is shown that cimetidine powder or medicinal liquid has no adverse reaction, small side effects, and is effective for epidermis wounds. Hemostasis, short healing time, obvious effect on ulcer repair and scar removal, and low cost.

Description

technical field [0001] The invention relates to a new application of cimetidine, in particular to the application of cimetidine in the preparation of medicaments for treating wounds from epidermis to papillary dermis. Background technique [0002] Skin trauma is a common disease. Trauma is divided into closed wound and open wound. Open wound refers to the rupture of the skin and mucous membrane at the injured site with open wound and external bleeding, accompanied by deep tissue damage, mainly including Cuts, superficial skin abrasions, punctures and lacerations, etc. Different medications are used for different depths of the wound. At present, there are many medicines for the treatment of epidermal wounds, but there are few medicines for repairing epidermal wounds, the treatment time is long, the curative effect is not significant, and the price of the medicines is relatively expensive. [0003] Cimetidine is a common drug that has been widely used clinically. The molec...

Claims

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Application Information

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IPC IPC(8): A61K31/4164A61P17/02
Inventor 麻正义周治德蒋代荣李桂银方成陈真诚刘铭兴唐卫民
Owner GUILIN UNIV OF ELECTRONIC TECH
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