Dynamic Tracking of Moving Targets

Abstract

Dynamic tracking of moving targets. Treatment targets, such as tumors or lesions, located in an anatomical region that undergoes motion (which may be cyclic motion with cycles P) are dynamically tracked. Build a 4D mathematical model of non-rigid motion and deformation of an anatomical region from a set of CT or other 3D images. The 4D mathematical model relates the 3D position of the portion of the anatomical region to the target being tracked as a function of position in time in P. Determine the absolute position of targets and / or other parts of an anatomical region using fiducial-less, non-rigid image alignment between pre-operative DRR and intra-operative x-ray images. Cycle P is determined using a motion sensor such as a surface marker. Release the radiation beam using: 1) the result of non-rigid image alignment; 2) the 4D model; and 3) the position in time in P.

Description

Background technique In some medical applications, objects moving over time must be dynamically tracked. For example, in radiosurgery, it may be necessary to dynamically track tumors and / or lesions in a human body as it moves with breathing and / or heartbeat. In radiosurgery, the precise trajectory of the radiation beam through the patient anatomy to the lesion or tumor to be treated is critical in order to achieve the radiation dose distribution calculated during the treatment planning period. For areas of the human anatomy that move, for example due to breathing or heartbeat, it is important to take such movements into account and calculate their influence on the treatment plan to be produced. Motion tracking can also benefit other medical applications outside of radiosurgery, where parts of an anatomy move due to breathing, heartbeat, or any other type of motion. In the past, fiducial markers have been used to facilitate tracking of moving regions of anatomy. Baseline bas...

AI Technical Summary

Problems solved by technology

These methods do not account for the non-rigid motion and deformation of the surrounding anatomy as a function of the motion period

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