Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Manufacturing method of superparamagnetic magnesium-doped ferrite nanoparticles and the nanoparticles

A nanoparticle and magnesium ferrite technology, applied in nanostructure manufacturing, in vivo test preparations, nanomagnetism, etc., can solve problems such as insufficient research, and achieve the effect of improving effective imaging diagnostic technology

Inactive Publication Date: 2011-11-30
NURI VISTA
View PDF2 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to recent reports, due to the high magnetic susceptibility, high self-heating (~120°C) and high biocompatibility (cell survival rate of 90%) of several magnesium-based alloys or oxide nanoparticles with a size of several nm to several μm, Therefore, the possibility of being used as a hyperthermia agent is very high, but the research related to nanoparticles with a size below 10nm that can actually be injected into the human body is not sufficient, and it has not been applied to hyperthermia agents (hyperthermia agent) and Heat shock protein derivatives and the application technology for clinical treatment of brain tumors, optic nerve diseases, cranial nerve diseases and other diseases

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Manufacturing method of superparamagnetic magnesium-doped ferrite nanoparticles and the nanoparticles
  • Manufacturing method of superparamagnetic magnesium-doped ferrite nanoparticles and the nanoparticles
  • Manufacturing method of superparamagnetic magnesium-doped ferrite nanoparticles and the nanoparticles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] Such as figure 1 Shown, the manufacture method of the superparamagnetic magnesium-doped ferrite nano-particle of processing of the present invention, comprises the steps: in raw material triacetylacetonate iron (Fe (III) acetylacetonate), magnesium and reducing agent (reduction, hexadecanediol, After mixing benzyl ether (Benzyl ether) and oleic acid (Oleic acid) and oleylamine (Oleylamine) as surfactants in hexadecanediol), nucleation is generated by the first heat treatment, and the nanometer is made by the second heat treatment. After the particles are grown, they are washed, centrifuged, dried and ground.

[0023] Nanoparticles manufactured through the above series of processes were additionally coated with Tetraethylorthosilicate, chitosan, and D-glucose dextran.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention relates to a manufacturing method of engineered Mg doped ferrite superparamagnetic nanoparticles processed by doping magnesium and the technology of applying it to hyperthermia and heat shock protein derivation of self-defense mechanism .

Description

technical field [0001] The invention relates to a method for manufacturing superparamagnetic magnesium-doped ferrite (Mg doped ferrite) nanoparticles capable of processing high-temperature self-heating and an application thereof. The processed superparamagnetic Mg-doped ferrite nanoparticles manufactured according to the present invention can be applied to hyperthermia agents and self-defense mechanism heat shock protein derivatives against cancer in vivo, and thus can be applied to brain Clinical treatment of various diseases such as tumors, optic nerve diseases, and cranial nerve diseases. Background technique [0002] Hyperthermia is a treatment method that heats cancer cells at a temperature of 43°C to 45°C to cause apoptosis. While minimizing side effects, it is possible to selectively and effectively treat cancer cells (tissues) distributed locally or deeply in the human body, and the scope of research on its clinical feasibility is rapidly expanding. [0003] Especi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B82B3/00C01G49/00
CPCC01P2004/04C01P2002/72B82Y30/00B82Y5/00A61K49/183C01P2004/64C01G49/0036C01P2006/42A61K49/1863A61K41/0052B82Y25/00A61P25/00A61P27/02A61P27/06A61P35/00B82B3/00C01G49/00B82Y40/00
Inventor 裴成泰郑景元
Owner NURI VISTA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com