Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for extracting total flavonoids from cloverleaf by supercritical carbon dioxide

A technology of carbon dioxide and liquid carbon dioxide, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of large amount of extraction solvent, easy oxidative decomposition of products, and long time, so as to achieve short extraction cycle and high product quality. No loss, the effect of reducing the amount of solvent

Inactive Publication Date: 2011-11-30
NANJING ZELANG MEDICAL TECH
View PDF1 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These methods often have many problems such as large amount of extraction solvent, long time, serious pollution, and easy oxidation and decomposition of products due to high temperature.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Grind clover to 60-80 mesh, take 1kg and put it into a supercritical carbon dioxide extraction tank, set the pressure at 30MPa, temperature at 50°C, and feed in liquid carbon dioxide. 50% ethanol solution, the flow rate is 1L / h, extract for 3 hours, adjust the temperature of the separator to 55°C, and the pressure to 6MPa, analyze the extract to recover the ethanol solution, and dry to obtain 215g of total flavonoids with a content of 12%.

Embodiment 2

[0015] Crush clover to 60-80 mesh, take 1kg and put it into a supercritical carbon dioxide extraction tank, set the pressure at 20MPa, temperature at 40°C, and feed in liquid carbon dioxide. 70% ethanol solution, the flow rate is 1L / h, extract for 2 hours, adjust the temperature of the separator to 60°C, and the pressure to 8MPa, analyze the extract to recover the ethanol solution, and dry to obtain 202g of total flavonoids with a content of 17%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for extracting total flavonoids of A. trifoliate with supercritical carbon dioxide, which is characterized in that: A. trifoliate medicinal material is crushed into 60-80 meshes, added to a supercritical carbon dioxide extraction tank, fed with liquid carbon dioxide and an entrainer, and extracted at a pressure of 20 Under the conditions of -30MPa and temperature 40-50°C, extract for 2-3 hours, analyze the extract under reduced pressure in a separator, recover the reagent, and dry to obtain the total flavonoids of Clover. The method of the invention is simple in operation, high in efficiency, can reduce pollution, reduce the consumption of organic solvents, and is suitable for industrialized production.

Description

technical field [0001] The invention relates to a method for extracting total flavonoids of cloverleaf, in particular to a method for extracting total flavonoids of cloverleaf with supercritical carbon dioxide. Background technique [0002] Clover is the clover plant of Vitis vinaceae, and the whole plant can be used as medicine, and the medicinal effect of underground tubers and fruits is the best. Also known as snake aconite, golden thread hanging gourd, silk thread hanging golden bell, three-leaf flat rattan, stone mouse, small flat rattan, stone monkey, Tujing pill, and three-leaf pair. The nature and flavor are slightly bitter, flat, and have the effects of clearing heat and detoxifying, dispelling wind and resolving phlegm, promoting blood circulation and relieving pain. Studies have found that Clover has obvious curative effects on severe infectious diseases such as pneumonia, lymph node tuberculosis, hepatitis, gastritis, cervicitis, and sepsis. It has extensive an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61P35/00
Inventor 刘东锋杨成东
Owner NANJING ZELANG MEDICAL TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com