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New Chinese medicine for treating early and middle-stage diabetic nephropathy

A new drug, the technology of astragalus polysaccharide, applied in the field of medicine and health, can solve the problems that the characteristics and advantages of treatment have not been fully displayed, the lack of ideal drugs in treatment, and the curative effect is difficult to be fully exerted, etc.

Inactive Publication Date: 2011-11-02
田景振 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Traditional prescriptions have deficiencies in preparation technology, dosage form, drug loading, effective dose, compliance, etc., making it difficult to fully exert the curative effect of traditional Chinese medicine in the treatment of DN, and the characteristics and advantages of treatment have not been fully displayed. The current level of DN prevention and treatment is at In the state of entanglement and lingering, there has been a lack of ideal drugs for treatment, so the development of innovative drugs for the treatment of DN has become an urgent and important topic in current pharmaceutical research and development

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The ratio of astragalus saponins, astragalus polysaccharides, astragalus flavones, rhubarb total anthraquinones, icariin, epimedium polysaccharides, ligustrazine, and ferulic acid is 1:100:30:120:15:5:7:9 , adding appropriate auxiliary materials to make capsules.

Embodiment 2

[0015] The ratio of astragalus saponins, astragalus polysaccharides, astragalus flavonoids, rhubarb total anthraquinones, icariin, epimedium polysaccharides, ligustrazine, and ferulic acid is 1:60:20:90:10:5:6:8 , add appropriate excipients to make oral microemulsion.

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Abstract

The invention relates to a new Chinese medicine for treating early and middle-stage diabetic nephropathy, which is prepared from eight medicinal effect ingredients: astragaloside, astragalan, astragalus flavone, rhubarb total anthraquinone, icraiin, epimedium polysaccharide, ligustrazine and ferulic acid according to a certain ratio. The new Chinese medicine has the specific treatment effect on the early and middle-stage diabetic nephropathy, and can be solid preparations such as tablets, capsules, granules, pills and the like and also can be liquid preparations such as oral liquid, emulsion, microemulsion, injection and the like.

Description

technical field [0001] The invention belongs to the field of medicine and health, and relates to a new traditional Chinese medicine for treating early and middle-stage diabetic nephropathy. Background technique [0002] Diabetic nephropathy (Diabetic nephropathy, DN ) is one of the most common and serious chronic complications of diabetes, and it is also the main cause of death in diabetic patients. Currently, about 30% to 50% of patients with type 1 diabetes and 5% to 10% of patients with type 2 diabetes are associated with obvious DN clinically, and about 1 / 3 of them further develop into advanced DN and end-stage renal disease. The resulting treatment costs not only bring a heavy economic burden to the family and society, but also seriously affect the patient's own survival and quality of life. With the aging of the world's population, economic development, and changes in people's lifestyles, the incidence of diabetes worldwide is on the rise, especially in China. There ...

Claims

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Application Information

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IPC IPC(8): A61K36/708A61P3/10A61P13/12A61K31/192
Inventor 田景振李万忠
Owner 田景振
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