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Medicine for treating rheumatoid arthritis and preparation method thereof

A technology for arthritis and rheumatism, applied in the field of traditional Chinese medicine, can solve the problems of small toxic and side effects, achieve quick results, good taste, and improve the effect of joint pain

Inactive Publication Date: 2011-11-02
WUHAN HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of treatment, there is currently no drug with ideal curative effect and little side effects

Method used

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  • Medicine for treating rheumatoid arthritis and preparation method thereof
  • Medicine for treating rheumatoid arthritis and preparation method thereof
  • Medicine for treating rheumatoid arthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Composition: Astragalus 1000g, Qingfengteng 500g, Scorpio 100g.

[0029] The above 3 raw materials are made into 1000 capsules altogether.

[0030] Preparation:

[0031] a. Take the bulk drug according to the weight ratio for subsequent use;

[0032] B. Scorpion is ground into fine powder after being dried, crosses 100 mesh sieves, mixes, and makes medicine fine powder (I);

[0033] c. Soak Astragalus membranaceus and Qingfengteng in water for 0.5 hours, then decoct twice, add 10 times the amount of water to decoct for 1.5 hours for the first time, add 8 times the amount of water to decoct for 1.0 hours for the second time, combine the decoction, Combine the decoctions, let stand for precipitation for 14 hours, filter, and concentrate the filtrate to extract (II) with a relative density of 1.30 at 60°C;

[0034] d. Get drug fine powder (I) and extract (II) and mix with ethanol, make soft material, granulate with 20 mesh sieves;

[0035] e. Drying: Dry the prepared w...

Embodiment 2

[0040] Composition: Astragalus 750g, Qingfengteng 375g, Scorpion 375g.

[0041] The above 3 raw materials are made into 1000 capsules altogether.

[0042] Preparation:

[0043] a. Take the bulk drug according to the weight ratio for subsequent use;

[0044] B. Scorpion is ground into fine powder after being dried, crosses 100 mesh sieves, mixes, and makes medicine fine powder (I);

[0045] c. Soak Astragalus membranaceus and Qingfengteng in water for 1 hour, then decoct twice, add 8 times the amount of water to decoct for 1 hour, add 10 times the amount of water to decoct for 2 hours for the second time, combine the decoction, Combine the decoctions, let stand for precipitation for 20 hours, filter, and concentrate the filtrate to an extract (II) with a relative density of 1.20 at 60°C;

[0046] d. Get drug fine powder (I) and extract (II) and mix with ethanol, make soft material, granulate with 20 mesh sieves;

[0047] e. Drying: Dry the prepared wet granules at 65°C, pass ...

Embodiment 3

[0050] Composition: Astragalus 800g, Qingfengteng 600g, Scorpion 200g.

[0051] The above 3 raw materials are made into 1000 capsules altogether.

[0052] Preparation:

[0053] a. Take the bulk drug according to the weight ratio for subsequent use;

[0054] B. Scorpion is ground into fine powder after being dried, crosses 100 mesh sieves, mixes, and makes medicine fine powder (I);

[0055] c. Soak Astragalus membranaceus and Qingfengteng in water for 1 hour, then decoct twice, add 10 times the amount of water for the first time and decoct for 2 hours, add 10 times the amount of water for the second time and decoct for 2 hours, combine the decoction, Combine the decoctions, let stand for precipitation for 20 hours, filter, and concentrate the filtrate to an extract (II) with a relative density of 1.35 at 60°C;

[0056] d. Get drug fine powder (I) and extract (II) and mix with ethanol, make soft material, granulate with 20 mesh sieves;

[0057] e. Drying: Dry the prepared we...

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Abstract

The invention discloses a medicine for treating rheumatoid arthritis and a preparation method thereof. The medicine is prepared form 5 to 60 parts by weight of Radix Astragali, 5 to 15 parts by weight of orienavine and 1 to 15 parts by weight of scorpion. The medicine composition provided by the invention can be utilized for treating rheumatoid arthritis and has the advantages of low cost, safetyfor taking, no toxic and side effect, and feasibility of long term use. The invention also discloses a preparation method of capsules containing the medicine. The capsules prepared by the preparationmethod has the advantages of no stinking smell of Chinese medicine materials, good taste, convenience for taking, fast disintegration speed which is faster than the disintegration speeds of a tablet and a pill, and fast release of medicines which are in the capsules, is not effected by an adhesive and a pressure and can diffuse fast in gastric juice to play effects fast.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a medicine for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (RA) is a multisystem inflammatory autoimmune disease mainly involving peripheral joints. The clinical features are pain and swelling of the affected joints, decreased function, continuous lesion, repeated attacks, and high disability rate (up to 40%). The joints of severe patients are fibrous or bony ankylosing, and they lose joint function due to muscle atrophy and spasm around the joints, making them unable to take care of themselves. In addition to joint symptoms, there may also be extra-articular or visceral damage, such as rheumatoid nodules, heart, lung, kidney, peripheral nerves, and eyes. Lesions are persistent and recurrent. Rheumatoid arthritis is a common and difficult clinical disease with a high disability rate, which directly affects ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/59A61P19/02A61P29/00A61K35/64A61K35/646
Inventor 张荒生张义生王进军李建武
Owner WUHAN HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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