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Device and system for locally delivering therapeutic agents

A therapeutic agent and local technology, which is applied in the field of devices and systems for local delivery of therapeutic agents, can solve problems such as poor compatibility of positioning equipment, and achieve the effect of improving the use effect

Active Publication Date: 2011-09-28
MICROPORT SINICA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] In view of this, the present invention provides a device and system for local delivery of therapeutic agents to solve the problem of poor compatibility of positioning equipment in devices for delivery of therapeutic agents in the prior art

Method used

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  • Device and system for locally delivering therapeutic agents
  • Device and system for locally delivering therapeutic agents
  • Device and system for locally delivering therapeutic agents

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0097] Implementation method 1 (treatment of myocardial infarction, connected with magnetic positioning equipment):

[0098] 1. After the patient is anesthetized, put the human heart in the best working area of ​​the magnetic field generator;

[0099] 2. The injection catheter is connected to the magnetic positioning equipment and electrophysiological equipment through the connecting tail wire;

[0100] 3. According to the routine operation of interventional surgery, the injection catheter is sent through the aorta to the left ventricle of the heart through femoral artery puncture;

[0101] 4. Slide the head electrode of the injection catheter in the left ventricle, collect points, and establish a geometric model of the left ventricle;

[0102] 5. After the geometric model is established, under the guidance of the positioning system, the tip of the injection catheter slides in the left ventricle to collect points, and the left ventricular potential map model is established; ...

Embodiment approach 2

[0108] Implementation method 2 (treatment of myocardial infarction, connected with electrical positioning equipment):

[0109] 1. Anesthetize the surgical patient;

[0110] 2. The injection catheter is connected to the electrical positioning equipment and electrophysiological equipment through the connecting tail wire;

[0111] 3. According to the routine operation of interventional surgery, the injection catheter is sent through the aorta to the left ventricle of the heart through femoral artery puncture;

[0112] 4. Slide the head electrode of the injection catheter in the left ventricle, collect points, and establish a geometric model of the left ventricle;

[0113] 5. After the geometric model is established, under the guidance of the positioning system, the tip of the injection catheter slides in the left ventricle to collect points, and the left ventricular potential map model is established;

[0114] 6. Select the area to be injected through the potential map model; ...

Embodiment approach 3

[0119] Implementation method 3 (treatment of myocardial infarction, without positioning equipment, connected with electrophysiological equipment):

[0120] 1. Anesthetize the surgical patient;

[0121]2. Observe the structure of the left ventricle of the heart after myocardial infarction with an echocardiographic diagnostic instrument to determine the area of ​​myocardial infarction;

[0122] 3. Connect the tail wire socket of the injection catheter system to the multi-channel physiological recorder;

[0123] 4. According to the routine operation of interventional surgery, the injection catheter is sent to the left ventricle of the heart through the femoral artery puncture through the aorta;

[0124] 5. The multi-channel physiological recorder monitors the heart rate changes of people, prevents abnormalities during the operation, and conducts imaging monitoring;

[0125] 6. After the injection catheter enters the left ventricle, use an echocardiography diagnostic instrument ...

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Abstract

The invention discloses a device for locally delivering therapeutic agents, which comprises a main body catheter, an injection catheter and an operating handle, wherein a head electrode and a plurality of ring electrodes are arranged on a bendable section of the main body catheter; the head electrode is connected with the ring electrodes through a lead; the other end of the lead is connected witha connecting tail line jack on the operating handle; and a magnetic field sensor is fixed on the head electrode and is connected with the connecting tail line jack on the operating handle through a lead thereon. The invention also discloses a system. The head electrode and the ring electrodes are arranged on the bendable section for collecting electric signals, and a doctor distinguishes a pathological area of a patient according to the signals. Due to the arrangement, the device is compatible with magnetic positioning equipment and electrical positioning equipment, a three-dimensional geometrical model and a three-dimensional potential model are established, and a therapeutic part is accurately determined. According to a bending control piece on the operating handle, bidirectional bending is realized, and the therapeutic part is convenient and accurate to select.

Description

technical field [0001] The present invention relates to the technical field of intracavitary injection, and more specifically, relates to a device and system for locally delivering a therapeutic agent. Background technique [0002] Myocardial infarction (English name is myocardial infarction, English abbreviation is MI) refers to the interruption of coronary blood flow on the basis of coronary artery disease, which causes severe and persistent acute ischemia in the corresponding myocardium, eventually leading to myocardial ischemia. Sexual necrosis. Due to the lack of regeneration ability of mature cardiomyocytes, the number of cardiomyocytes decreases after myocardial infarction, and the infarcted area is replaced by scar tissue with non-contractile function through fibrous tissue hyperplasia. In order to maintain the pumping function of the heart, the left ventricle will gradually change from oval to spherical to increase the volume of the left ventricle, resulting in deg...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M31/00
Inventor 虞奇峰罗七一刘翔孙毅勇
Owner MICROPORT SINICA CO LTD
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