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Biological constant temperature separating tank and separating method thereof

A separation tank and constant temperature technology, applied in the direction of fermentation, etc., can solve the problems of extractant toxicity, retention, real-time extraction without fermentation, etc., and achieve the effects of simplifying the extraction steps, ensuring the activity of acid production, and reducing environmental pollution

Inactive Publication Date: 2011-06-08
TIANJIN UNIV OF SCI & TECH
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Problems solved by technology

With the calcium salt method, a large amount of calcium sulfate by-products will be obtained at the end and this method cannot be used for in-situ separation, while solvent extraction, electrodialysis and ultrafiltration can be used for in-situ separation, but due to the toxicity of the extractant, electrodialysis Dialysis membrane is easily fouled and limited
Ion exchange resins are used for the separation of lactic acid due to their strong anti-pollution ability, but the existing ion exchange technology only stays in the treatment of the liquid after fermentation, without real-time extraction of fermentation
[0003] At present, there is no method for effectively separating lactic acid in fermentation broth, let alone such a device

Method used

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  • Biological constant temperature separating tank and separating method thereof
  • Biological constant temperature separating tank and separating method thereof
  • Biological constant temperature separating tank and separating method thereof

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Embodiment Construction

[0035] Specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0036] figure 1 It is a structural schematic diagram of the biological constant temperature separation tank of the present invention. Such as figure 1 Shown, the biological constant temperature separation tank of the present invention comprises the plexiglass tube (12) and the plexiglass tube (14) that are placed in the water tank (19), a U-shaped heater (13) that is positioned at the bottom center of the water tank, a The water tank (19) is connected with a thermostat (15) for controlling the temperature in the water tank, a pump (18) and several pipelines providing flow paths for the fermented liquid, and a plurality of valves for controlling the flow direction of the fermented liquid are arranged in the middle of the pipelines. The plexiglass tube (12) and the plexiglass tube (14) are arranged on both sides of the heater (13), and the ple...

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Abstract

The invention relates to a biological product separating device and a separating method thereof, in particular to a device for in-situ separation of lactic acid inhibiting a product and a separating method thereof. The separating device comprises a circular treatment path and a separating column attemperator, wherein a fermentation liquid to be treated is dipped from a fermentation tank, and the fermentation liquid returns to the fermentation tank after being treated with anion exchange resin; and the separating column attemperator controls the temperature to be identical to the fermentation temperature via a temperature controller so as to ensure that microbes can use the treated fermentation liquid in time for separation of next batch. By using the device, lactic acid can be removed from the fermentation liquid in time so that product inhibition caused by the lactic acid can be eliminated, and the smooth fermentation can be ensured.

Description

technical field [0001] The invention belongs to the technical field of in-situ separation of lactic acid, and relates to a device for separating organic acid products under constant temperature and a separation method thereof, more specifically, a device for effectively separating lactic acid in fermentation broth and methods. Background technique [0002] Lactic acid is an important multipurpose organic acid, widely used in food, medicine, chemical industry, tanning, textile, environmental protection and agricultural production and other fields. In situ product removal (ISPR) refers to a method to quickly remove the metabolites of the production cells, and its organic combination with fermentation is in situ product removal and fermentation. The traditional lactic acid production is to add a neutralizing agent such as calcium carbonate during the fermentation process, and then carry out a series of steps such as concentration, precipitation, and filtration. This process is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P7/56
Inventor 高强高年发王德培张健刘发保
Owner TIANJIN UNIV OF SCI & TECH
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