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Lactogenic traditional Chinese medicine composition and preparation method thereof

A technology for compositions and pharmaceutical preparations, applied in the field of medicine, can solve the problems of easily causing allergic reactions, unable to meet clinical medication requirements, and large side effects.

Inactive Publication Date: 2013-12-04
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although folk diet therapy is relatively common, its efficacy is uncertain, lacks scientific research support, and can easily cause allergic reactions
Acupuncture, massage, and medical equipment-assisted therapy are mostly auxiliary and should not be used routinely
[0004] In drug treatment, Western medicine lacks effective and targeted drugs in the treatment of postpartum hypogalactia, and often has relatively large side effects. Therefore, the current clinical medication is mainly based on traditional Chinese medicine prescriptions, decoction treatment, and patients feel pain when taking medicine. not good
In addition, pangolin, an animal medicinal material, is added to the prescriptions of domestically approved prolactin-promoting Chinese patent medicines such as Tongru Granules and Xiaruyongquan San. However, pangolin is a national second-class precious and protected animal, which cannot meet the needs of clinical medicine.
Proved by long-term experiments, the drugs for promoting lactation that are currently on the market have poor stability, large side effects, and relatively expensive prices.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0093] Embodiment 1, pharmaceutical composition of the present invention

[0094] Bupleurum 10g, Baishao 10g, Scutellaria baicalensis 6g, Leulu 10g,

[0095] Tongcao 6g, Chuanxiong 10g, Wang Buliuxing 15g

[0096]Above-mentioned crude drug is processed into through following method:

[0097] (1) Radix Bupleurum and Rhizoma Chuanxiong were extracted twice with 8 times the amount of 70% ethanol, the first time was 2 hours, the second time was 1 hour, the extracts were combined and ethanol was recovered to obtain a concentrated solution;

[0098] (2) Scutellaria baicalensis is decocted twice with 8 times the amount of water, each time for 1 hour, and the filtrate is combined, adjusted to pH 1.5-2.0 with dilute hydrochloric acid, kept at 80°C for 1 hour, left at room temperature for 24 hours, filtered, and used for precipitation Wash with ethanol and water to pH 5-6, and dry to obtain the extract of Scutellaria baicalensis;

[0099] (3) Radix Paeoniae Alba, Leulu, Tongcao, and ...

Embodiment 2

[0101] Embodiment 2, pharmaceutical composition of the present invention

[0102] Bupleurum 3g, Paeoniae Alba 3g, Scutellaria baicalensis 2g, Leulu 3g,

[0103] Tongcao 2g, Chuanxiong 3g, Wang Buliuxing 5g

[0104] Above-mentioned crude drug is processed into through following method:

[0105] (1) Radix Bupleurum and Rhizoma Chuanxiong were extracted twice with 8 times the amount of 50% ethanol, each time for 1 hour, the extracts were combined and ethanol was recovered to obtain a concentrated solution;

[0106] (2) Scutellaria baicalensis is decocted twice with 8 times the amount of water, each time for 1 hour, and the filtrate is combined, adjusted to pH 1.5-2.0 with dilute hydrochloric acid, kept at 80°C for 1 hour, left at room temperature for 24 hours, filtered, and used for precipitation Wash with ethanol and water to pH 5-6, and dry to obtain the extract of Scutellaria baicalensis;

[0107] (3) Radix Paeoniae Alba, Leulu, Tongcao, and Wangbuliuxing were extracted twi...

Embodiment 3

[0109] Embodiment 3, pharmaceutical composition of the present invention

[0110] Bupleurum 30g, Paeoniae Alba 30g, Scutellaria baicalensis 18g, Leulu 30g,

[0111] Tongcao 18g, Chuanxiong 30g, Wang Buliuxing 45g.

[0112] Above-mentioned crude drug is processed into through following method:

[0113] (1) Radix Bupleurum and Rhizoma Chuanxiong were extracted 3 times with 10 times the amount of 80% ethanol, each time for 3 hours, the extracts were combined and ethanol was recovered to obtain a concentrated solution;

[0114] (2) Scutellaria baicalensis is decocted with 10 times the amount of water for 3 times, each time for 3 hours, the filtrate is combined, adjusted to pH 1.5-2.0 with dilute hydrochloric acid, kept at 80°C for 1 hour, left at room temperature for 24 hours, filtered, and used for precipitation Wash with ethanol and water to pH 5-6, and dry to obtain the extract of Scutellaria baicalensis;

[0115] (3) Radix Paeoniae Alba, Leulu, Tongcao, and Wangbuliuxing we...

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PUM

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Abstract

The invention relates to a lactogenic traditional Chinese medicine composition and a preparation method thereof. The composition consists of radix bupleuri, radix paeoniae alba, scutellaria baicalensis, radix rhapontici, tetrapanax papyriferus, ligusticum wallichii and the seed of cowherb.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition with prolactin effect and a preparation method thereof. Background technique [0002] With the development of science and technology and the improvement of people's living standards, more and more attention has been paid to breastfeeding; but at the same time, due to the acceleration of people's life rhythm and the increase of life pressure, postpartum lactation insufficiency has gradually increased among women, especially urban women. Statistics from 20 provinces (municipalities) in my country show that the lactation rate only accounts for 44% in the 4 months postpartum period. One of the core issues in improving the rate of breastfeeding is to promote and maintain breastmilk secretion. According to the theory of traditional Chinese medicine for the type diagnosis of postpartum lactation insufficiency to treat based on syndrome differentiation....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P15/14
Inventor 颜璐璐周水平马晓慧周桂荣周王谊万梅绪李欣欣
Owner TIANJIN TASLY PHARMA CO LTD
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