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Traditional Chinese medicine composition with galactagogue effect and preparation method thereof

A technology of composition and pharmaceutical preparation, applied in the field of medicine, can solve the problems of poor compliance, large side effects, uncertain curative effect and the like

Inactive Publication Date: 2011-05-11
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although folk diet therapy is relatively common, its efficacy is uncertain, lacks scientific research support, and can easily cause allergic reactions
Acupuncture, massage, and medical equipment-assisted therapy are mostly auxiliary and should not be used routinely
[0004] In drug treatment, Western medicine lacks effective and targeted drugs in the treatment of postpartum hypogalactia, and often has relatively large side effects. Therefore, the current clinical medication is mainly based on traditional Chinese medicine prescriptions, decoction treatment, and patients feel pain when taking medicine. not good
In addition, pangolin, an animal medicinal material, is added to the prescriptions of domestically approved prolactin-promoting Chinese patent medicines such as Tongru Granules and Xiaruyongquan San. However, pangolin is a national second-class precious and protected animal, which cannot meet the needs of clinical medicine.
Proved by long-term experiments, the drugs for promoting lactation that are currently on the market have poor stability, large side effects, and relatively expensive prices.

Method used

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  • Traditional Chinese medicine composition with galactagogue effect and preparation method thereof
  • Traditional Chinese medicine composition with galactagogue effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0094] Embodiment 1, pharmaceutical composition of the present invention

[0095] Astragalus 15g Angelica 10g Rehmannia 15g

[0096] Wangbuliuxing 15g Pig's trotter armor 15g Passepartout 6g

[0097] Above-mentioned crude drug is processed into through following method:

[0098] (1) Angelica sinensis was extracted twice with 8 times the amount of 75% ethanol, each time for 2 hours, the extracts were combined, filtered, concentrated and then added with water 4 times the weight of the medicinal material, refrigerated overnight, filtered, and concentrated to obtain a supernatant;

[0099] (2) Rehmannia glutinosa, Astragalus membranaceus, Wang Buliuxing, Trotter and Passepartout add 8 times the amount of water to extract twice, the first time is 1.5 hours, the second time is 1 hour, and the combined filtrate is concentrated to a relative density of 1.00-1.15 , add ethanol for alcohol precipitation, the concentration of alcohol precipitation is 70%, take the supernatant and conce...

Embodiment 2

[0102] Embodiment 2, pharmaceutical composition of the present invention

[0103] Astragalus 15g Angelica 10g Rehmannia 15g

[0104] Wangbuliuxing 15g Pig's trotter armor 15g Passepartout 6g

[0105] Above-mentioned crude drug is processed into through following method:

[0106] (1) Angelica sinensis was extracted twice with 6 times the amount of 60% ethanol, each time for 3 hours, the extracts were combined, filtered, concentrated and then added with water 5 times the weight of the medicinal material, refrigerated overnight, filtered, and concentrated to obtain a supernatant;

[0107] (2) Rehmannia glutinosa, Astragalus membranaceus, Wang Buliuxing, Trotter and Passepartout were extracted twice with 6 times the amount of water, each time for 3 hours, the combined filtrate was concentrated to a relative density of 1.00-1.15, added ethanol for alcohol precipitation, and alcohol The sinking concentration is 70%, just take the supernatant and concentrate;

[0108] (3) the above ...

Embodiment 3

[0110] Embodiment 3, pharmaceutical composition of the present invention

[0111] Astragalus 5g Angelica 3g Rehmannia 5g

[0112] Wang Buliu Xing 5g Trotter Armor 5g Passepartout 2g

[0113] Above-mentioned crude drug is processed into through following method:

[0114] (1) Angelica is extracted twice with 8 times the amount of 80% ethanol, each time for 1 hour, the extracts are combined, filtered, concentrated and then added with water 3 times the weight of the medicinal material, refrigerated overnight, filtered, and concentrated to obtain a supernatant;

[0115] (2) Rehmannia glutinosa, Astragalus membranaceus, Wang Buliuxing, Trotters and Passepartout were extracted twice with 8 times the amount of water, each time for 2 hours, the combined filtrate was concentrated to a relative density of 1.00-1.15, added ethanol for alcohol precipitation, and alcohol The sink concentration is 80%, just take the supernatant and concentrate;

[0116] (3) the above two parts of the supe...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition with a galactagogue effect and a preparation method thereof, and the composition comprises membranous milkvetch root, Chinese angelica, radix rehmanniae preparata, cowherb seed, pig nails and beautiful sweetgum fruit.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition with prolactin effect and a preparation method thereof. Background technique [0002] With the development of science and technology and the improvement of people's living standards, more and more attention has been paid to breastfeeding; but at the same time, due to the acceleration of people's life rhythm and the increase of life pressure, postpartum lactation insufficiency has gradually increased among women, especially urban women. According to the theory of traditional Chinese medicine for the type diagnosis of postpartum lactation insufficiency to treat based on syndrome differentiation. At present, the two types are mainly Qi and blood deficiency and liver depression and Qi stagnation. Due to the increasing rate of caesarean section, overnutrition and unbalanced maternal nutrition, the number of puerperas with weak qi and blood hypogalact...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P15/14A61K35/36
Inventor 周桂荣颜璐璐周水平周王谊莫红梅马晓慧栗志文
Owner TIANJIN TASLY PHARMA CO LTD
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