Application of hexachlorophene in resistance to Eimeria tenella

Abstract

The invention discloses an application of hexachlorophene in preparation of a drug resistant to Eimeria tenella. The hexachlorophene and pharmaceutically acceptable excipients are evenly mixed and added in water or feed. The animal infection experiments confirm that the anticoccidial index (ACI) of the hexachlorophene reaches over 168.8, and the hexachlorophene has better effect in resistance to the Eimeria tenella.

Description

technical field [0001] The invention relates to a new application of hexachlorophene, in particular to the application of hexachlorophene in resisting Eimeria tenella. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers the intensive chicken industry production, and the economic loss caused by it is as high as more than 2.5 billion pounds every year. The most harmful is Eimeria tenella. Although my country has no accurate statistics on this so far, the most conservative estimate is that the loss should not be less than 2.5 billion RMB. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Hexachlorophene (Hexachlorophene), chemical name, 2,2'-methylene bis(3,4,6-trichlorophenol), also known as methylene trichlorophene; toad...

AI Technical Summary

Problems solved by technology

[0005] Hexachlorophene has good antibacterial effect on Gram-positive bacteria, but poor effect on Gram-negative bacteria, and has no effect on Mycobacterium tuberculosis and spores

[0007] So far, there has been no report on the effect of hexachlorophene against Eimeria tenella, and it is impossible to infer whether hexachlorophene has an anti-Eimeria tenae effect based on the known properties of hexachlorophene

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