Method for regenerating a derma tissue by utilizing fat mesenchymal cell

Abstract

One purpose of the invention is to provide a method and a formula, which is characterized in that mesenchymal stem cells from an autologous fat cell tissue are proliferated by in-vitro culture, then is mixed into a support material and finally is transplanted into the body of a patient; the fat mesenchymal cell in a transplant is differentiated to derma fibroblast under the action of the local microenvironment, the newly generated derma fibroblast can further activate secretion of cell collagenstroma at an injection part so as to carry out reproductive repair on coloboma and aging of human skin tissue. The application scope of the invention includes: subcutaneous padding for face lift, subcutaneous padding cosmetology, subcutaneous padding for repairing depressed deletion or impairment and the like. Seed cells utilized in the invention are prepared by separating and purifying the fat tissues of the patients, so that ethical disputes and immunological rejection reaction are avoided. The fat tissues can be obtained by the instrument suction method; and the operation of the method is simple, patients suffer from minor damages and pains.

Description

technical field [0001] The invention relates to a method for dermis regeneration by utilizing the multidirectional differentiation potential of human adipose mesenchymal cells combined with tissue engineering technology, which is suitable for plastic surgery and cosmetic surgery, and belongs to the field of tissue engineering. Background technique [0002] Anti-aging is a topic of common concern to all mankind. Most of the substances that support human skin exist in the dermis. A fiber network composed of collagen, elastic fibers and hyaluronic acid supports the skin, and its content determines the texture of the skin. All three are secreted by fibroblasts in the dermis: fibroblasts constantly secrete collagen, elastin fibers, and hyaluronic acid to maintain skin's radiance and texture. After the age of 25, fibroblasts decrease at a rate of 1% to 2% per year, followed by a decrease in the number of collagen, elastic fibers and hyaluronic acid, showing signs of aging. The a...

AI Technical Summary

Problems solved by technology

[0010] Tissue engineering scaffold materials provide seed cells with a three-dimensional biological space similar to extracellular matrix, which is suitable for cell growth and differentiation, and overcomes the disadvantages of poor cell survival and low matrix synthesis ability in previous single cell transplantation.

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