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Herbal composition for osteoarthritis

A technology of herbal medicine and agarwood, which can be used in anti-inflammatory agents, bone diseases, medical formulas, etc., and can solve problems such as uncertain effectiveness

Active Publication Date: 2011-01-26
SAGITTARIUS LIFE SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some food supplements such as Glucosamine (Glucosamine), Chondroitin Sulfate (Chondroitin Sulfate) clinical effectiveness has not been established, there are currently no drugs that modify the disease process

Method used

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  • Herbal composition for osteoarthritis
  • Herbal composition for osteoarthritis
  • Herbal composition for osteoarthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 1500 grams of lettuce, 150 grams of agarwood, 600 grams of rice, 150 grams of frankincense, 75 grams of Atractylodes macrocephala, and 150 grams of dodder were heated in 3 liters of deionized water at 100±5°C for 2.5 hours. The extract was collected. Repeat again. The secondary extracts were combined and passed through a 100-mesh sieve. The extract is concentrated and then sprayed and dried into powder (SO101C).

[0022] Experiment 1: Stimulation of Chondrocyte Proliferation

[0023] Human cartilage was obtained from joint replacement surgery with the informed consent of the patient. The cartilage was treated with bacterial secondary / quaternary collagenase (Collagenase, Worthington Chemical, Freehold, NJ) 1 mg / ml DMEM+10% fetal calf serum (FCS)+25 μg / ml Gentamicin (Gentamicin, Grand Island, NY) (C-DMEM) was digested overnight at 37°C, and the obtained cells were cultured in C-DMEM with 5% carbon dioxide at 37°C at high density.

[0024] 1×10 per hole 4 The cells we...

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PUM

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Abstract

A novel herbal composition comprising of Lactuca sativa L., Aquilariae resinatum Lignum, Oryza sativa L., Boswellia carterii Birdw, Rhizoma atractylodis macrocephalae and Semen cuscutae is useful in treating osteoarthritis.

Description

technical field [0001] A herbal compound containing lettuce, agarwood, rice, frankincense, atractylodes macrocephala, and dodder is used to treat osteoarthritis. Background technique [0002] More people suffer from osteoarthritis than any other joint disease. According to the 2005 statistics of the US Centers for Disease Control and Prevention (CDC), 13.9% of Americans over the age of 25 are affected by osteoarthritis, while 33.6% (12,400,000) of people over the age of 65 are affected. In 1997 an estimated $79 million was spent on knee and hip replacement surgery. In 2000, the estimated annual cost of treatment was $5,700. Work-related osteoarthritis cost between $34,000 and $132,000,000 per year ( www.cdc.gov / arthritis / osteoarthritis.html ). In the western world, 7-18% of elderly people have symptoms of knee osteoarthritis, while in China, 15% of women over 60 years old and 6% of men have osteoarthritis (Lai, H-Y, et.al., Intra-articular hyaluronic acid for treatment of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P19/02
CPCA61K36/284A61K36/899A61K36/28A61K36/835A61K36/43A61K36/324A61P19/02A61P29/00A61K2300/00
Inventor 刘素莹
Owner SAGITTARIUS LIFE SCI
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