Implantable human blood glucose concentration continuous monitoring system based on optical fiber attenuation total reflection

Abstract

The invention discloses an implantable human blood glucose concentration continuous monitoring system based on optical fiber attenuation total reflection, consisting of double optical paths and comprising a light source, an attenuator, a spectroscope, an optical fiber coupling device, an optical fiber ATR sensor, a measurement photodetector, a reference photodetector, a data collection system and a computer, wherein after being attenuated by the attenuator, the light source is divided into two optical paths formed by a measurement light and a reference light; in one optical path, the measurement light enters the optical fiber ATR sensor in a coupling way through a coupling method by the optical fiber coupling device and is received by the measurement photodetector via a transmission light of the optical fiber ATR sensor; in the other optical path, the reference light is directly received by the reference photodetector; signals recevied by the measurement photodetector and the reference photodetector are synchronously collected by the data collection system, are sent to the computer and are in analysis treatment, and the computer displays a measurement result and is also connected with the light source. The invention adopts a direct measurement in vivo method to directly measure the glucose concentration in a tissue fluid, thereby avoiding an error of measurement in vitro.

Description

technical field [0001] The invention relates to a device for continuously monitoring blood sugar concentration of a human body. In particular, it relates to an implantable human blood sugar concentration continuous monitoring system based on optical fiber attenuated total reflection, which uses an optical fiber ATR sensor implanted in the human body to measure the glucose concentration in the subcutaneous tissue fluid to continuously detect the blood sugar concentration of the human body. Background technique [0002] Diabetes is a common and frequently-occurring disease among middle-aged and elderly people. The World Health Organization lists it together with tumors and cardiovascular and cerebrovascular diseases as the three major difficult diseases within the scope. [0003] However, there is currently no clinical medical method to completely cure diabetes. The goal of current diabetes treatment is to achieve insulin control as much as possible, avoid hyperglycemia in th...

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Problems solved by technology

However, the flaws and deficiencies of the interstitial fluid extraction minimally invasive blood glucose detection method also make this method of Heise unable to be applied in clinical practice.

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