Chinese medicinal composition with effects of promoting blood circulation, regulating menstruation and relieving pain, and preparation method thereof

Abstract

The invention discloses a Chinese medicinal composition with the effects of promoting blood circulation, regulating menstruation and relieving pain, and a preparation method thereof. The composition consists of 2 to 30 parts of nutgrass galingale rhizome subjected to processing with rice vinegar, 5 to 60 parts of Chinese angelica and 2 to 30 parts of rhizoma corydalis subject to the processing with the rice vinegar. In the invention, the optimal proportional combination of the Chinese angelica, the nutgrass galingale rhizome subject to the processing with the rice vinegar and the rhizoma corydalis subject to the processing with the rice vinegar is determined by intensively studying a great number of ancient and modern formulae and performing screening by pharmacological activity experiments according to Chinese medicinal theories and dysmenorrhea pathogenesis to discard the dross, select the essential and simplify the formula. Compared with the equal amount of single Chinese angelica, single nutgrass galingale rhizome subject to the processing with the rice vinegar and single rhizoma corydalis subject to the processing with the rice vinegar, the Chinese medicinal composition provided by the invention is proved by the experiments to have remarkably prolonged in-vitro coagulation time, an anti-platelet aggregation function and the functions of more remarkably suppressing the contraction of uterine smooth muscles and preventing dysmenorrhea, and also is proved not to be the simple combination of quantities but to have synergism and great importance in guiding the clinical administration of the formulae.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition with functions of promoting blood circulation, regulating menstruation and relieving pain and a preparation method thereof. Background technique [0002] Dysmenorrhea is one of the most common symptoms in gynecology, and about 75% of women have dysmenorrhea. Dysmenorrhea is divided into two categories: primary and secondary; primary dysmenorrhea refers to cramping pain in the lower abdomen and waist before and during menstruation, accompanied by nausea, vomiting, and cold extremities in severe cases, especially in unmarried young women . Epidemiological studies have shown that primary dysmenorrhea is the most common disease in gynecology at present. The proportion of women with primary dysmenorrhea reported abroad is as high as 43% to 90%. The incidence rate of dysmenorrhea reported in China is 33.1%, of which primary dysmen...

AI Technical Summary

Problems solved by technology

Epidemiological studies have shown that primary dysmenorrhea is the most common disease in gynecology at present. The proportion of women with primary dysmenorrhea reported abroad is as high as 43% to 90%. The incidence rate of dysmenorrhea reported in China is 33.1%, of which primary dysmenorrhea accounts for 53.2%. Traditional Chinese medicine has a long history of treating gynecological diseases. Its treatment principle is to attack the evils and treat the symptoms when they occur, and strengthen the body when it does not occur. From the current clinical treatment of primary dysmenorrhea, the combination of syndrome differentiation and disease has become more and more unique in traditional Chinese medicine. However, most of the compound medicines currently used for the treatment of dysmenorrhea have multiple ingredients, large dosage, inconvenient use, complex ingredients, unclear effective parts, unclear material basis for the curative effect of the compound, and certain adverse reactions. Therefore, under the guidance of the theory of traditional Chinese medicine, it is very necessary to select a kind of drug that is simple in proportion, accurate in curative effect, small in side effects, convenient to take, and used for promoting blood circulation, regulating menstruation, and relieving pain under the guidance of the theory of traditional Chinese medicine.

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