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Compound resveratrol anti-inflammatory and itching relieving medicament combination and purpose thereof

A technology of resveratrol and medicine, which is applied in the treatment of dermatitis, eczema, itching caused by mosquito bites and its uses, can solve problems such as physical and mental health hazards, and achieve considerable social and economic benefits and unique curative effects

Inactive Publication Date: 2010-09-15
LOGISTICS UNIV OF CAPF
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It brings serious harm to the physical and mental health of patients. Therefore, research and development of a low-cost eczema external preparation that has good antipruritic effect, fast disappearance of skin lesions, and is not easy to recur, does not pollute clothes, and can save traditional Chinese medicine resources is of great importance. practical significance

Method used

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  • Compound resveratrol anti-inflammatory and itching relieving medicament combination and purpose thereof
  • Compound resveratrol anti-inflammatory and itching relieving medicament combination and purpose thereof
  • Compound resveratrol anti-inflammatory and itching relieving medicament combination and purpose thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of a medicine for treating dermatitis eczema and itching caused by mosquito bites:

[0026] Glycyrrhizic acid 10g artemisinin 10g, menthol 1g, appropriate amount of ointment base (glycerol monostearate 60g, petrolatum 40g, cetyl alcohol 30g, liquid wax 4g, glycerin 70g, Span-60, Tween-80, nitrogen Ketones, preservatives, flavors in moderation)

[0027] Put 60g of glyceryl monostearate, 40g of vaseline, 30g of cetyl alcohol, 4g of liquid wax, and Span-60 into a beaker and mix them, and heat them in a water bath to 80-90°C to melt. Glycyrrhizic acid and artemisinin are completely dissolved by adding an appropriate amount of ethanol, then mixed into the oil phase, and the ethanol is evaporated until there is no alcohol smell.

[0028] Add 70g of glycerin, Tween-80, and 10g of matrine into purified water and heat to 70-80°C. Under the condition of constant stirring, slowly add the water phase into the oil phase, stop heating, when it cools down to about 60°C, ...

Embodiment 2

[0031] Preparation of a medicine for treating dermatitis eczema and itching caused by mosquito bites:

[0032] Glycyrrhetinic acid 10g, artesunate 10g, borneol 0.5g, ointment base amount (glycerol monostearate 60g, petrolatum 40g, cetyl alcohol 30g, liquid wax 4g, glycerin 70g, Span-60, Tween- 80, azone, preservatives, fragrance amount)

[0033] Put 60g of glyceryl monostearate, 40g of vaseline, 30g of cetyl alcohol, 4g of liquid wax, and Span-60 into a beaker and mix them, and heat them in a water bath to 80-90°C to melt. Glycyrrhetinic acid and artemisinin are completely dissolved by adding an appropriate amount of ethanol, then mixed into the oil phase, and the ethanol is evaporated until there is no alcohol smell.

[0034] Add 70g of glycerin and Tween-80 into purified water and heat to 70-80°C. Under the condition of constant stirring, slowly add the water phase into the oil phase, stop heating, when it cools down to about 60°C, add azone and preservatives under constan...

Embodiment 3

[0036] Preparation of a medicine for treating dermatitis eczema and itching caused by mosquito bites:

[0037] Glycyrrhetinic acid 10g, artemisinin succinate 10g, borneol 0.5g, appropriate amount of ointment base (glyceryl monostearate 60g, petrolatum 40g, cetyl alcohol 30g, liquid wax 4g, glycerin 70g, Span-60, Tween -80, azone, preservatives, flavor amount)

[0038] Put 60g of glyceryl monostearate, 40g of vaseline, 30g of cetyl alcohol, 4g of liquid wax, and Span-60 into a beaker and mix them, and heat them in a water bath to 80-90°C to melt. Glycyrrhetinic acid and artemisinin are completely dissolved by adding an appropriate amount of ethanol, then mixed into the oil phase, and the ethanol is evaporated until there is no alcohol smell.

[0039] Add 70g of glycerin and Tween-80 into purified water and heat to 70-80°C. Under the condition of constant stirring, slowly add the water phase into the oil phase, stop heating, when it cools down to about 60°C, add azone and preser...

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PUM

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Abstract

The invention provides a pure traditional Chinese medicine compound preparation for external use (such as ointment, film agent, gel and tincture), which is used for treating pruritus caused by eczema-dermatitis and mosquito biting and does not contain hormonal. The compound is prepared from resveratrol, glycyrrhizic acid or physiologically acceptable salts of glycyrrhizic acid or glycyrrhetinic acid or physiologically acceptable salts of glycyrrhetinic acid, ginghaosu and derivates thereof, menthol or borneol composition. Proved by experiments and clinical tests, the compound resveratrol anti-inflammatory and itching relieving medicament combination has the functions of resisting inflammation, restraining bacteria and relieving itching aiming at the characteristics of pruritus caused by eczema-dermatitis and mosquito biting and has specific curative effect for pruritus caused by eczema-dermatitis and mosquito biting. The invention has the advantages of nontoxic raw materials, low price and cost, wide market prospect and considerable expectant economic benefit and social benefit.

Description

technical field [0001] The invention relates to a pharmaceutical composition and its use, in particular to a medicine for treating dermatitis eczema and itching caused by mosquito bites and its use. Background technique [0002] Eczema is an inflammatory skin disease with obvious exudation tendency caused by various internal and external factors, and is a common multiple skin disease. Its clinical features are pleomorphic rash, exudative tendency, symmetrical distribution, infiltration and hypertrophy in the chronic phase, consciously severe pruritus, and easy recurrence of the disease, which may not heal for many years. Dermatitis and eczema are often mentioned together because they describe the same disease from different angles. The main symptoms of dermatitis and eczema are itching and rash. However, there is still a difference between dermatitis and eczema. The so-called clinical dermatitis refers to eczema with definite etiology or certain characteristics. Most of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/704A61K31/366A61K31/045A61K31/56A61K31/357A61K31/05A61K9/06A61P17/04A61P17/00
Inventor 张静泽李覃陈虹安茜曹波白淑芳刘岱琳高颖
Owner LOGISTICS UNIV OF CAPF
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