Use of CLEC1B for the determination of cardiovascular and thrombotic risk

Abstract

The use of the single nucleotide polymorphism (SNP) of the CLEC1B gene for the identification of cardiovascular and / or thrombotic disorders or of an increased risk for developing cardiovascular and / or thrombotic disorders in a biological sample taken from an individual to be examined; the use of CLEC1B for identifying substances active in preventing and / or treating cardiovascular and / or thrombotic disorders and methods for doing so.

Description

Use of CLEC1B to identify cardiovascular and thrombotic risk technical field The present invention relates to the use of single nucleotide polymorphisms (SNPs) and protein polymorphisms in identifying increased risk of cardiovascular and / or thrombotic disorders and primers and nucleic acids suitable for said use. Furthermore, the present invention relates to the discovery of CLEC1B (C-type lectin domain family 1, member B or alternatively C-type lectin-like receptor 2 / CLEC-2, hereinafter referred to as CLEC1B) for the prevention and treatment of cardiovascular and use in active substances for thrombotic disorders. Background technique Cardiovascular and / or thrombotic disorders are among the leading causes of death in both sexes in Western countries. Cardiovascular disorders include all disorders affecting the function of the heart, including in particular cardiac tissue and cardiovascular disorders. Thrombotic disorders include all pathological conditions affecting blood...

AI Technical Summary

Problems solved by technology

As a result, the patient or attending physician is often unaware of possible damage to heart tissue until the damage ultimately results in a myocardial infarction

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