Compound cornu cervi degelatinatum preparation as well as preparation method and application thereof

A deer horn cream and compound technology, applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., can solve problems such as dependence, large toxic side effects on the human body, and incomplete treatment

Inactive Publication Date: 2014-04-16
FIRST CLINICAL MEDICAL SCI COLLEGE OF CHINA THREE GORGES UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing drugs for treating rheumatoid arthritis are mainly hormone drugs, which cannot be completely cured, have great toxic and side effects on the human body, and easily form drug dependence

Method used

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  • Compound cornu cervi degelatinatum preparation as well as preparation method and application thereof
  • Compound cornu cervi degelatinatum preparation as well as preparation method and application thereof
  • Compound cornu cervi degelatinatum preparation as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] Take 200g of antler cream, 800g of deer's grass, 800g of Sansevieria root, 200g of dew honeycomb, 200g of mulberry branch, and 200g of cassia twig;

[0106] Crush 200g of cassia twig into a coarse powder, put it in a round-bottomed flask, add 9 times the amount of water, soak for 2 hours, and extract with reference to a steam distillation device to obtain cinnamon twig volatile oil for later use;

[0107] Remove the dead pupae from 200g of dew hives, crush them, put them in a volatile oil extractor, add 10 times the amount of water, heat them in a constant temperature water bath at 70°C, reflux, cool, extract for 12 hours, and collect the oily matter for later use;

[0108] Put cinnamon sticks and hive residues into the total medicinal materials for alcohol extraction;

[0109] Extract the antler cream, deerbite, Sansevieria verticillium root, and mulberry branch fine powder with 20 times 60% ethanol three times at a temperature of 80°C for 6 hours each time, collect th...

Embodiment 2

[0130] Take 500g of deer horn cream, 800g of deer's grass, 800g of Sansevieria root, 800g of dew hive, 300g of mulberry branch, and 300g of cassia twig;

[0131] Crush 300g of cassia twig into a coarse powder, put it in a round-bottomed flask, add 10 times the amount of water, soak for 2 hours, and extract with reference to a steam distillation device to obtain cinnamon twig volatile oil for later use;

[0132] Remove the dead pupae of 800g dew hives, crush them, put them in a volatile oil extractor, add 10 times the amount of water 1, heat them in a constant temperature water bath at 70°C, reflux, cool, extract for 12 hours, and collect the oily matter for later use;

[0133] Put cinnamon sticks and hive residues into the total medicinal materials for alcohol extraction;

[0134] Use 20 times 60% ethanol to extract three times with 20 times of 60% ethanol, extract 6 hours each time, collect the total extract, concentrate to obtain extract, dry to obtain extract pink.

[013...

Embodiment 3

[0155] Take 300g of antler cream, 600g of deer's grass, 600g of Sansevieria root, 100g of honeycomb, 200g of mulberry branch, and 200g of cassia twig;

[0156] Crush 300g of cassia twig into a coarse powder, put it in a round-bottomed flask, add 10 times the amount of water, soak for 2 hours, and extract with reference to a steam distillation device to obtain cinnamon twig volatile oil for later use;

[0157] Remove the dead pupae of 600g dew hives, crush them, put them in a volatile oil extractor, add 10 times the amount of water, heat them in a constant temperature water bath at 70°C, reflux, cool, extract for 12 hours, and collect the oily matter for later use;

[0158] Put cinnamon sticks and hive residues into the total medicinal materials for alcohol extraction;

[0159] Use 20 times 60% ethanol to extract three times with 20 times of 60% ethanol, extract 6 hours each time, collect the total extract, concentrate to obtain extract, dry to obtain extract pink.

[0160] T...

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Abstract

The invention relates to a compound cornu cervi degelatinatum preparation prepared into tablets or capsules or oral liquid pharmaceutical dosage forms together with a proper pharmaceutical carrier from cornu cervi degelatinatum, herba pyrolae, crinite uraria roots, nidus vespae, mulberry twigs and cassia twigs by a alcohol extraction method; and particularly, the invention relates to a preparation method of the tablets. With another purpose, the invention provides application of the compound cornu cervi degelatinatum preparation in preparing medicines for treating rheumatoid arthritis diseases. The compound cornu cervi degelatinatum preparation can effectively treat rheumatoid arthritis, also gradually reduce the usage amount of hormones in the treatment process of the rheumatoid arthritis and finally replace the hormones, has reasonable prescription and low toxic side effect and is economical and practical.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a compound antler cream preparation and a preparation method and application thereof. Background technique [0002] Rheumatoid arthritis (RA) is a common systemic autoimmune disease with chronic, symmetrical polysynovial arthritis and extra-articular lesions (subcutaneous nodules, pleurisy, pneumonia, etc.) as the main clinical manifestations. The basic pathological change is synovitis, which in turn causes bone destruction and erosion. In the late stage, it can lead to joint deformity and severe functional impairment, which brings great suffering to patients and a heavy burden on society. It is a common and frequently-occurring disease. The prevalence rate in my country is 0.3% to 0.4%. If it is not diagnosed and treated in time, the average life expectancy will be shortened by 10 to 15 years, and 70% of patients may become disabled after 2 years, leading...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/605A61P19/02A61P19/04A61P29/00A61K35/64A61K35/32
Inventor 王燕燕杨俊刘红兵彭艳崔向军周刚
Owner FIRST CLINICAL MEDICAL SCI COLLEGE OF CHINA THREE GORGES UNIV
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