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X ray phase contrast tomography

A phase-contrast imaging and X-ray technology, applied in the field of X-ray radiation imaging, can solve problems such as low contrast and tissue stacking, and achieve the effects of reducing dose, improving quality, and fast and simple inspection process

Active Publication Date: 2010-06-09
TSINGHUA UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In particular, for example for medical breast imaging, it can solve the problems of tissue lamination and low contrast in conventional mammography methods, and obtain higher contrast images under low irradiation dose conditions, thereby improving the quality of the obtained tomographic images

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0122] A specific embodiment of X-ray phase-contrast tomography is given below by taking the scanning manner of an arc track as an example.

[0123] In the case of this embodiment, the object to be inspected remains fixed, and the X-ray source is fixed on the same support as the detector of the grating subsystem (including double gratings) and the detection unit, as above Figure 10 shown. The source, grating subsystem, and detector remain relatively stationary during data acquisition. In order to meet the parameter requirements of formula (4), it is necessary to adjust the distance between the X-ray source and the double grating. This can be done by fixing the ray source and the second grating B, and adjusting the position of the first grating A in the Z direction. The movement of the first grating A in the Z direction can be completed by controlling the actuating structure of the control device of the system, and the precision is on the order of microns. Similarly, the X-...

Embodiment 2

[0128] In an exemplary case, the detector portion of the detection unit and the grating subsystem remain stationary while the ray source moves linearly, as in Figure 11a , 11b shown. In this case, the mechanical movement of the system is simpler. Compared with the arc track scanning method, its effective scanning angle is smaller under the condition of detectors of the same size.

[0129] During the data acquisition process of a position state, the inspected object (such as mammary gland), the double grating and the detector remain stationary, and the ray source moves in a straight line, such as Figure 11a shown. Wherein, the ray source can move on the trajectory at equal intervals, or in an equiangular manner. In the equiangular mode, the movement interval of the object is determined by the angular interval θ and the distance L from the ray source to the sample, H=Lsinθ. In the fixed detector scanning mode, the angular sampling interval θ is smaller than that of the ar...

Embodiment 3

[0134] This embodiment describes the linear trajectory scanning mode, which is characterized in that the ray source, the grating subsystem and the detector remain relatively stationary, and move relatively linearly with the object to be detected, as shown in FIG. 12 . In this mode, the system structure is simple and does not contain relatively complex rotation movements. Depending on the application environment, such as Figure 12a As shown, there are two equivalent methods for the linear trajectory method: the ray source and the grating subsystem remain stationary, and the sample moves along a linear trajectory; the sample does not move, and the ray source and the grating subsystem remain relatively stationary and perform linear motion.

[0135] Taking the first movement mode as an example, the object to be inspected moves on a linear trajectory, stops at different positions and remains still, completes a phase step scan, and obtains one or more projection images through info...

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Abstract

The invention relates to an X ray phase contrast imaging system and an X ray phase contrast imaging method. The system comprises an X ray device, a grating system, a detection unit, a data processing unit and a relative shifting device, wherein the X ray device emits X ray bundles to a detected object; the grating system comprises a first absorption grating and a second absorption grating and is positioned on a direction of an X ray, and the X ray refracted by the detected object forms a variable-intensity X ray signal through the first absorption grating and the second absorption grating; the detection unit receives the variable-intensity X ray signal and converts the variable-intensity X ray signal into an electrical signal; the data processing unit processes and extracts the refraction angle information in the electrical signal and computes pixel information by utilizing the refraction angle information; and the relative shifting device is used for enabling the detected object to relatively shift relative to the imaging system. The imaging system carries out phase contrast imaging for the detected object within a certain relative shifting range of the imaging system and the detected object at a plurality of positions so as to obtain a plurality of images of the detected object. The images are converted into the images on the same reconstruction plane so as to carry out three-dimensional image reconstruction.

Description

[0001] Related references [0002] This application hereby incorporates the entire content of the previous Chinese patent application No. 2008100057663 as a reference. technical field [0003] The invention relates to the field of X-ray radiation imaging, in particular to tomographic imaging of phase contrast of objects by X-rays. Background technique [0004] Commonly used X-ray imaging generally utilizes the attenuation properties of X-rays by material materials to non-destructively inspect the internal structure of objects. Conventional X-ray imaging techniques are especially effective if the density of the structural composition of the various parts inside the object differs significantly. However, substances composed of light elements such as hydrogen, carbon, nitrogen and oxygen are weak absorbers for X-rays, so the detailed structure inside them can hardly be seen with traditional X-ray imaging techniques. Even with other auxiliary means, such as imprinting contrast...

Claims

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Application Information

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IPC IPC(8): G01N23/083G01N23/04
Inventor 张丽黄志峰陈志强王振天李元景赵自然肖永顺邢宇翔
Owner TSINGHUA UNIV
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