Anti-sunstroke application of baicalin

Abstract

The invention relates to an anti-sunstroke application of baicalin (beta-D-gluconic acid-5,6-dihydroxy-4-oxo-2-phenyl-4H-benzopyran-7). Under the condition of oral administration, the baicalin can obviously delay the sunstroke of rats in the thermal environment, extend the survival time of the rats suffering from sunstroke and put off the death of the rats in the thermal environment. The inventor feeds adult rats baicalin of certain concentration by intragastric administration, then observes the sunstroke and the survival time of the rats, and discovers that feeding the rats the baicalin of certain concentration by intragastric administration can obviously delay the sunstroke of the rats in the thermal environment, put off the death of the rats in the thermal environment, simultaneously extend the survival time of the rats suffering from sunstroke, and improve the anti-sunstroke capability of the rats. When feeding a proper amount of common medicant baicalin at the proper time by the method, the anti-thermal injury capability of the rats can be improved, thereby providing strong evidences to human experiments. When the baicalin is applied to human bodies, better economic benefits and social benefits can be obtained.

Description

technical field [0001] The invention relates to an anti-heat stroke application of baicalin. Under the condition of oral administration, baicalin can significantly delay the occurrence of heatstroke in rats in hot environment, prolong the survival time of heatstroke rats, and delay the death of rats in hot environment. Background technique [0002] Preventive measures for thermal environment damage and heatstroke are important topics in environmental medicine, military medicine, and aerospace medicine. So far, there is still no satisfactory drug for preventing heatstroke. [0003] Baicalin is one of the main components extracted from the dry root of Scutellaria baicalensis Georgi, a plant in the Labiatae family, and it is the component with the strongest pharmacological effect among the active ingredients of Scutellaria baicalensis. Baicalin (C 21 h 18 o 11 ), has pharmacological effects such as clearing heat and detoxifying, antibacterial and anti-inflammatory, chelatin...

AI Technical Summary

Problems solved by technology

Intraperitoneal injection of baicalin is effective. Although it shows that baicalin has important pharmacological effects, it is extremely inconvenient to use and has no obvious prospect in the human body.

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