Medicament combination for preventing and treating canine/feline magnesium ammonium phosphate stones, and preparation method thereof

Abstract

The invention relates to a medicinal composition for preventing and treating canine / feline magnesium ammonium phosphate stones, and a preparation method thereof. The composition is prepared by evenlymixing the following effective components in ratio by weight or unit: 13 to 39 grams of lysimachia nummularia and lygodium japonicum granules, 0.3 gram of acetohydroxamic acid and 4,000 IU of vitaminA. The medicinal composition for preventing and treating canine / feline magnesium ammonium phosphate stones is added as a unit for each kilogram of canine / feline feed. In the invention, lysimachia nummularia promotes urination and treats stranguria, while lygodium japonicum clears heat, promotes urination, treats stranguria and relieves pain, and both the lysimachia nummularia and the lygodium japonicum can increase the frequency of ureteral peristalsis, raise the pressure in ureteral upper-section cavities and play a significant role in promoting urination and eliminating stones; meanwhile, the agent utilizes the characteristic of inhibiting urease activity through acetohydroxamic acid to reduce the ammonia concentration and pH of urine and prevent the formation of infectious urinary stones or inhibit the growth thereof; and the vitamin A is utilized to maintain the integrity of urinary-tract epithelium so as to realize the activity of crystallization inhibitors and inhibit crystallization. The agent jointly uses medicaments from different angles to eliminate the inducing factors of stones and plays a definite role in preventing magnesium ammonium phosphate stones.

Description

technical field [0001] The invention relates to a medicine for preventing and treating calculus in dogs and cats and a preparation method thereof, in particular to a pharmaceutical composition for preventing and treating calculus of ammonium magnesium phosphate in dogs and cats and a preparation method thereof. Background technique [0002] In recent years, dogs and cats have become the mainstream of pets, and working dogs and meat dogs have driven the development of the entire dog industry. In the breeding and management of dogs and cats, disease is the most important link that affects the health of dogs and cats. Among them, dog and cat urolithiasis is the most common urinary system disease in dogs and cats. According to domestic and foreign research data, its clinical incidence rate is 0.5-1.0%, and the recurrence rate of urolithiasis within two years after treatment can be as high as 50%. . The pathogenesis of stones is complicated, and there are many types of stones, ...

AI Technical Summary

Problems solved by technology

Some foreign pet food companies have developed a series of prescription diets for the prevention and treatment of dog and cat stones, but the price is generally high and it is difficult to widely sell them