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Veterinary compound apramycin sulfate soluble powder and application thereof

A soluble technology of apramycin sulfate, applied in powder delivery, pharmaceutical formula, organic active ingredients, etc., can solve the problem of reducing curative effect, achieve the effect of reducing drug resistance, reducing the amount of antibiotics, and widely used

Inactive Publication Date: 2010-02-17
天津市海纳德动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, farmers used macrolides or quinolones as the first choice for the treatment of yellow and white scour of piglets, but these conventional drugs were often used repeatedly, which made the pathogenic microorganisms resistant to the drugs and reduced the curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Weigh the raw materials according to the following proportions: 15g of apramycin sulfate, 5g of colistin sulfate, 0.15g of atropine sulfate, 3mg of epidermal growth factor (EGF), add oral glucose to 100g, and mix evenly to make a treatment for piglets. Specific drugs for yellow and white diarrhea. The raw materials are all commercially available products.

[0019] The pharmaceutically applicable adjuvant is one of sucrose, anhydrous glucose and oral glucose, or any combination of two or more.

Embodiment 2

[0021] Weigh the raw materials according to the following proportions: 5g of apramycin sulfate, 7g of colistin sulfate, 0.1g of atropine sulfate, 2mg of epidermal growth factor, add anhydrous glucose to 100g, mix well and serve.

[0022] Others are with embodiment 1.

Embodiment 3

[0024] Weigh the raw materials according to the following proportions: 25g of apramycin sulfate, 10g of colistin sulfate, 0.2g of atropine sulfate, 5mg of epidermal growth factor, add sucrose and anhydrous glucose to 100g, mix well and serve.

[0025] Others are with embodiment 1.

[0026] Application examples:

[0027] Application of veterinary compound apramycin sulfate soluble powder in the treatment of yellow and white scour of piglets.

[0028] In June 2008, there were 3 litters (5-15 days old) of piglets in a pig farm in Hebei Province, and a total of 23 piglets became ill one after another. According to clinical symptoms and laboratory test results, it was diagnosed as pathogenic E. white diarrhea. After treatment, except for 2 piglets that died and the other 2 piglets died of serious illness, all the others recovered.

[0029] The specific analysis is as follows:

[0030] (1) Onset and clinical symptoms

[0031] At the beginning of June 2008, 3 litters of 5-15-day...

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PUM

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Abstract

The invention relates to veterinary compound apramycin sulfate soluble powder and application thereof. The veterinary compound apramycin sulfate soluble powder is characterized by being prepared by mixing the following components according to unit weight of 100g: 3-25g of apramycin sulfate, 5-10g of colistin sulfate, 0.1-0.2g of atropine sulfate, 2-5mg of epidermal growth factor, and the balance of medically applicable auxiliary materials. The components with optimal contents are as follows: 15g of apramycin sulfate, 5g of colistin sulfate, 0.15g of atropine sulfate, 3mg of epidermal growth factor, and the balance of medically applicable auxiliary materials, wherein the auxiliary materials comprise more than one of sucrose, anhydrous glucose and oral glucose. The invention also discloses the application of the veterinary compound apramycin sulfate soluble powder to treatment of piglet yellow-white scour. By adopting the compound preparation of antibiotics, anticholinergics and epidermal growth factors, the invention has effective treatment effect for piglet yellow-white scour, has the efficacy of treating both the symptoms and root cause and reduces the bacterial resistance probability with simple preparation, obvious effect and wide application.

Description

technical field [0001] The invention relates to a veterinary drug and application thereof, in particular to a traditional Chinese medicine for treating yellow and white scour of piglets, that is, veterinary compound apramycin sulfate soluble powder and application thereof. Background technique [0002] Piglet yellow and white scour is a common and frequently-occurring disease widely existing in pig farms. It not only brings a lot of drug expenditure to the breeding industry, but also directly affects the growth and development of piglets; it is mainly caused by pathogenic Escherichia coli. infectious disease. Yellow dysentery occurs mostly in suckling piglets less than 1 week old, 1-3 days old is the most common, and piglets over 7 days old are rarely affected; yellow or gray-yellow watery feces are discharged with diarrhea, and the onset is acute and dehydrated rapidly. It is characterized by weakness and death; the morbidity rate is usually above 90%, and the mortality ra...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K9/14A61P31/04A61P1/12A61K38/12A61K31/46A61K31/7036
Inventor 伦艳霞
Owner 天津市海纳德动物药业有限公司
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