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Medicine composition and preparation method thereof

A composition and medicine technology, applied in the field of pharmaceutical compositions and their preparation, can solve the problems that the clinical efficacy is inferior to decoction, the dosage of the preparation is large, and the patient's compliance is poor, and the effect of no adverse reactions and toxic side effects can be achieved.

Active Publication Date: 2009-11-11
广西厚德大健康产业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many Chinese patent medicines for the treatment of stranguria, but due to the limitation of historical conditions, the preparation process of Chinese patent medicines has not been studied in depth, resulting in too many extracts, large dosage of preparations, and poor patient compliance, resulting in generally inferior clinical curative effect to decoctions. The advantages of patented medicines have not been fully utilized

Method used

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  • Medicine composition and preparation method thereof
  • Medicine composition and preparation method thereof
  • Medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] Guangshen grass 1500g Centella asiatica 500g Hedyotis diffusa 500g Astragalus 500g Shiwei 500g Jinsha rattan 500g Polygonum cuspidatum 250g

[0089] Add water to decoct the above raw materials twice, add 8 times and 6 times of water in turn, each time for 1 hour, filter, combine the filtrate, concentrate to 25-40 liters, pass through the microfiltration of 0.2 μm ceramic membrane, collect the filtrate, and concentrate to 60 liters. The clear paste with a relative density of 1.30 at ℃ is dried, pulverized, an appropriate amount of lactose is added, mixed evenly, made into granules, dried, an appropriate amount of magnesium stearate is added, mixed evenly, and pressed into tablets.

[0090] For patients with stranguria syndrome caused by damp-heat accumulation, take 3 tablets orally, 3 times a day.

Embodiment 2

[0092] Guangshen grass 1200g Centella asiatica 350g Hedyotis diffusa 400g Astragalus 350g Shiwei 350g Jinsha rattan 380g Polygonum cuspidatum 200g

[0093] Add water to decoct the above raw materials twice, add 15 times of water each time, 1 hour each time, filter the extract, concentrate the filtrate to a clear paste with a relative density of 1.25 at 60°C, dry, crush, add an appropriate amount of starch, and mix well. Pack into capsules to make hard capsules.

[0094] For patients with stranguria syndrome who have symptoms of stranguria and pain, take 3 capsules orally, 3 times a day.

Embodiment 3

[0096] Guangshen grass 900g Centella asiatica 300g Hedyotis diffusa 300g Astragalus 300g Shiwei 300g Jinsha rattan 300g Polygonum cuspidatum 150g

[0097] The above raw materials were decocted three times with water, followed by adding 12 times, 10 times, and 10 times of water, the first time was 1.5 hours, the second time was 1 hour, and the third time was 1 hour, the extract was filtered, and the filtrate was concentrated to a relative density of 1.20 ( 60°C) extract, add ethanol to make the alcohol content reach 70%, let it stand, filter, recover ethanol, concentrate to a clear paste with a relative density of 1.18 at 60°C, dry, pulverize, add dextrin and sucrose in an appropriate amount, Made into granules, made into granules.

[0098] Patients with urinary tract infection take orally, 1 bag at a time, 3 times a day.

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Abstract

The invention discloses a medicine composition which is mainly prepared from desmodium styracifolium, asiatic centella, oldenlandia diffusa, milk veteh, pyrrosia lingua, lygodium japonicum and giant knotweed. The medicine composition has the efficacy of clearing away heat and toxic materials as well as removing dampness and treating stranguria, and is used for stranguria, difficulty and pain in micturition and urinary tract infection which are caused by damp heat accumulation; and the adaptation diseases include frequent urination, urgent urination, dysuria, dark yellow urine and urinary tract infection. The medicine composition can be prepared into various oral liquid.

Description

field of invention [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating stranguria syndrome caused by damp-heat accumulation, stranguria and astringent pain, and urinary tract infection and a preparation method thereof. Background technique [0002] The stranguria syndrome is a common and frequently-occurring disease in clinical practice, with frequent urination, urgency, painful urination and incessant urination as the main symptoms, among which hot stranguria is the most common. Urinary system diseases mainly seen in Western medicine, such as urinary system infections including lower urinary tract infections (cystitis, urethritis) and upper urinary tract infections (pyelonephritis), rank second only to respiratory tract infections among infectious diseases 2, the incidence rate in the population accounts for 2%, and it is more common in women and the elderly. The incidence ...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P13/00
Inventor 唐弟光阮碧芳莫少红李品黄园陈晓军梁月钊梁山丹吴伟粱尚焕蒙华英
Owner 广西厚德大健康产业股份有限公司
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