Skull repairing material and preparation method thereof

Abstract

The invention discloses a skull repairing material which is provided with a titanium mesh bracket. The surface of the titanium mesh bracket is provided with a film layer consisting of hydroxylapatite and titanium dioxide, and one side of the titanium mesh bracket is provided with a bionic layer. The skull repairing material has biological activity, a TiO2 ceramic film layer containing HAP generated on the surface of a titanium mesh through micro-arc oxidation plays a role of biological activity, and HAP in human tissue fluid and skull edges are tightly combined with TiO2 under the role of -OH to reach the function of cell bonding. The bionic layer below the titanium mesh bracket can play a role of cold insulation, heat insulation, shock prevention and buffer, and the entire product is humanized and scientific.

Description

technical field [0001] The invention relates to a skull injury repairing material, in particular to a bionic skull repairing material and a preparation method thereof. Background technique [0002] The skull is one of the most important parts of the human skeleton. It protects and supports the brain receptors, forms the cranial cavity that houses the brain, and supports the cranial surface. Once a skull injury occurs, it will bring great pain to the patient, not only affect the appearance, but also make the patient feel insecure, and even cause various adverse consequences such as skull defect syndrome, brain atrophy, and traumatic epilepsy. At present, there are many repair materials for skull defects, such as plexiglass, hydroxyapatite (HAP) materials, titanium mesh, etc., each with its own advantages and disadvantages. Plexiglass has poor biocompatibility and is not widely used clinically; HAP materials have good biocompatibility, but the manufacturing cost is high, and ...

AI Technical Summary

Problems solved by technology

Plexiglass has poor biocompatibility and is not widely used clinically; HAP materials have good biocompatibility, but the manufacturing cost is high, and HAP is gradually absorbed by the human body over time, and its strength will decrease; the most widely used clinically It is a titanium mesh, which has good biocompatibility and sufficient strength, and is easy to make, but the above products have common shortcomings in clinical applications:

[0005] 2. Biological activity cannot be reflected

The adverse result that can be produced is that the screw or steel wire fixing the titanium mesh compresses the edge of the skull for a long time, causing local bone ischemia in the skull, resulting in osteoporosis, bone resorption, and then causing nail removal, mesh loosening, mesh displacement, etc. Occurrence of adverse events

[0007] Chinese patent 200720119254.0 discloses a titanium mesh for skull repair, which includes a top surface and a bottom surface, and there are a number of through mesh nail holes between the top surface and the bottom surface. The mesh nail holes are arranged in rows and columns, and the mesh nail holes are square through holes. Combining with conical countersunk holes interpenetrating with each other, the titanium mesh for skull repair described in this patent cannot play the role of shockproof, sound insulation, and cushioning, and has no biological activity

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